Intratumour hypoxia is a feature of all heterogenous solid tumours. Increased levels or
subregions of tumour hypoxia are associated with an adverse clinical prognosis, particularly …

Simple Summary Localized prostate cancer has a favorable prognosis and can be
effectively treated with radiotherapy, as well as therapies that target hormone production and …

Metastatic castration-resistant prostate cancer remains incurable regardless of recent
therapeutic advances. Prostate cancer tumors display highly glycolytic phenotypes as the …

Cellular plasticity in prostate cancer promotes treatment resistance. Several independent
studies have used mouse models, single-cell RNA sequencing, and genetic lineage tracing …

Hypoxia elicits a multitude of tissue responses depending on the severity and duration of the
exposure. While chronic hypoxia is shown to impact development, regeneration, and cancer …

Purpose of review The role of the microbiome in prostate cancer is an emerging subject of
research interest. Certain lifestyle factors, such as obesity and diet, can also impact the …

Abstract Background: Abnormal expression of Zinc finger (ZNF) genes is commonly
observed in osteosarcoma (OS), the most prevalent malignant bone tumor in children and …

Prostate cancer is a prevalent malignancy that is frequently managed with radiotherapy.
However, resistance to radiotherapy remains a significant challenge in controlling this …

The human kallikrein-related peptidase (KLK) family which consists of 15 members is
associated with prostate cancer and other cancers. It has been reported that overexpression …

In 2024, prostate cancer (PCa) remains the most common non-skin cancer in males within
the United States, with an estimated 299,010 new cases, the highest increase incident trend …