Genomic landscape of cancer in racially and ethnically diverse populations

CE Thomas, U Peters - Nature Reviews Genetics, 2024 - nature.com
Cancer incidence and mortality rates can vary widely among different racial and ethnic
groups, attributed to a complex interplay of genetic, environmental and social factors …

A new view of activating mutations in cancer

R Nussinov, CJ Tsai, H Jang - Cancer research, 2022 - AACR
A vast effort has been invested in the identification of driver mutations of cancer. However,
recent studies and observations call into question whether the activating mutations or the …

Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia

A Stiff, M Fornerod, BN Kain, D Nicolet, BJ Kelly… - Nature …, 2024 - nature.com
Genomic profiles and prognostic biomarkers in patients with acute myeloid leukemia (AML)
from ancestry-diverse populations are underexplored. We analyzed the exomes and …

Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study

NP Tjader, AJ Beer, J Ramroop, MC Tai… - Cancer research …, 2024 - aacrjournals.org
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype
and ancestry. Emerging data suggest tumor mutation status is associated with germline …

[CITA][C] Linking Germline And Somatic Gene Regulatory Processes In Lung Cancer

ATZ Khoo - 2023 - ResearchSpace@ Auckland