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[HTML][HTML] A structural overview of the ion channels of the TRPM family
The TRPM (transient receptor potential melastatin) family belongs to the superfamily of TRP
cation channels. The TRPM subfamily is composed of eight members that are involved in …
cation channels. The TRPM subfamily is composed of eight members that are involved in …
Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration
Objectives The co-occurrence of melanoma and Parkinson's disease (PD) is higher than
expected. We review the relationship between melanoma and PD, then proffer a hypothesis …
expected. We review the relationship between melanoma and PD, then proffer a hypothesis …
Biometal dyshomeostasis and toxic metal accumulations in the development of Alzheimer's disease
Y Li, Q Jiao, H Xu, X Du, L Shi, F Jia… - Frontiers in molecular …, 2017 - frontiersin.org
Biometal dyshomeostasis and toxic metal accumulation are common features in many
neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease, and …
neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease, and …
TRP channels role in pain associated with neurodegenerative diseases
M Duitama, V Vargas-López, Z Casas… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
Structural pharmacology of TRP channels
Y Zhao, BM McVeigh, VY Moiseenkova-Bell - Journal of molecular biology, 2021 - Elsevier
Transient receptor potential (TRP) ion channels are a super-family of ion channels that
mediate transmembrane cation flux with polymodal activation, ranging from chemical to …
mediate transmembrane cation flux with polymodal activation, ranging from chemical to …
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer's disease
S Zhang, F Cao, W Li, N Abumaria - Science signaling, 2023 - science.org
Altered abundance or activity of the dual-function transient receptor potential melastatin-like
7 (TRPM7) protein is implicated in neurodegenerative disorders, including Alzheimer's …
7 (TRPM7) protein is implicated in neurodegenerative disorders, including Alzheimer's …
TRPM2 Promotes Neurotoxin MPP+/MPTP-Induced Cell Death
In neurons, Ca 2+ is essential for a variety of physiological processes that regulate gene
transcription to neuronal growth and their survival. 1-methyl-4-phenyl-1, 2, 3, 6 …
transcription to neuronal growth and their survival. 1-methyl-4-phenyl-1, 2, 3, 6 …
TRP channels: role in neurodegenerative diseases and therapeutic targets
TRP (Transient receptor potential) channels are integral membrane proteins consisting of a
superfamily of cation channels that allow permeability of both monovalent and divalent …
superfamily of cation channels that allow permeability of both monovalent and divalent …
Long non-coding RNA-p21 regulates MPP+-induced neuronal injury by targeting miR-625 and derepressing TRPM2 in SH-SY5Y cells
XM Ding, LJ Zhao, HY Qiao, SL Wu… - Chemico-biological …, 2019 - Elsevier
Abstract Parkinson's disease (PD), the second most prevalent age-related
neurodegenerative disease, occurs as a result of the loss of dopaminergic neurons in the …
neurodegenerative disease, occurs as a result of the loss of dopaminergic neurons in the …
[HTML][HTML] Lipids as central modulators of sensory TRP channels
MG Ciardo, A Ferrer-Montiel - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
The transient receptor potential (TRP) ion channel family is involved in a diversity of
physiological processes including sensory and homeostatic functions, as well as muscle …
physiological processes including sensory and homeostatic functions, as well as muscle …