Opportunities for the Application and Advancement of the Corey–Chaykovsky Cyclopropanation

GL Beutner, DT George - Organic Process Research & …, 2022 - ACS Publications
Cyclopropanes are a common motif in many pharmaceutically relevant compounds, and
methods for the synthesis of these strained rings have relevance throughout the …

Recent advances in asymmetric synthesis via cyclopropanol intermediates

M Laktsevich-Iskryk, A Hurski, M Ošeka… - Organic & Biomolecular …, 2025 - pubs.rsc.org
Cyclopropanols have gained significant attention in organic synthesis as versatile three-
carbon synthons, as this readily available class of donor-activated cyclopropanes undergo …

Unveiling the Beauty of Cyclopropane Formation: A Comprehensive Survey of Enantioselective Michael Initiated Ring Closure (MIRC) Reactions

R Moorthy, W Biosawe, SS Thorat… - Organic Chemistry …, 2024 - pubs.rsc.org
This review presents a comprehensive overview of the synthesis of cyclopropanes using
enantioselective Michael Initiated Ring Closure (MIRC) reaction. Cyclopropane-containing …

General Synthesis of Cyclopropanols via Organometallic Addition to 1-Sulfonylcyclopropanols as Cyclopropanone Precursors

RM Rivera, Y Jang, CM Poteat, VNG Lindsay - Organic Letters, 2020 - ACS Publications
The addition of organometallic reagents to ketones constitutes one of the most
straightforward synthetic approaches to tertiary alcohols. However, due to the absence of a …

Photocatalytic Stoichiometric Oxidant-Free Synthesis of Linear Unsaturated Ketones from 1, 2-Disubstituted Cyclopropanols

MV Laktsevich-Iskryk, AV Krech, VN Zhabinskii… - …, 2021 - thieme-connect.com
A one-step catalytic oxidant-free synthesis of unsaturated ketones from 1, 2-disubstituted
cyclopropanols is reported. Previously for this transformation, only two-and three-step …

Synthesis and Applications of Cyclopropanones and Their Equivalents as Three-Carbon Building Blocks in Organic Synthesis

Y Jang, R Machín-Rivera, VNG Lindsay - Synthesis, 2021 - thieme-connect.com
Cyclopropanone derivatives constitute highly strained cycloalkanones with promising
applications as three-carbon building blocks in organic synthesis. Due to the presence of a …

Electrochemical Cyclopropanation of Unactivated Alkenes with Methylene Compounds

M Liu, Y Wang, C Gao, J Jia, Z Zhu, Y Qiu - Angewandte Chemie - Wiley Online Library
Cyclopropanes are prevalent in natural products, pharmaceuticals, and bioactive
compounds, functioning as a significant structural motif. Although a series of methods have …

Chirogenesis in Asymmetric Synthesis and Catalysis

DG Kananovich, M Lopp - Chirogenesis In Chemical Science, 2023 - World Scientific
Methods of asymmetric synthesis and catalysis are briefly reviewed and illustrated with
selected examples, together with a short historical sketch. Particular attention is paid to the …

[图书][B] Controlled α–Halogenation of Alkyl Sulfones and Stereospecific Ring-Expansion of Cyclopropanones

CM Poteat - 2021 - search.proquest.com
Pharmaceuticals containing the sulfone functionality are often found to exhibit diverse
therapeutic properties, justifying the development of more efficient synthetic methods for the …

Addition Reactions: Polar Addition

P Kocovský - Organic Reaction Mechanisms 2017: An annual …, 2020 - Wiley Online Library
During the coverage period of this chapter, reviews and highlights have appeared on the
following topics: Markovnikov selectivity of electrophilic additions of HF and HCl to non …