DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts

PC Logan, MD Mitchell, PE Lobie - Frontiers in genetics, 2013 - frontiersin.org
Specialized cell types of trophoblast cells form the placenta in which each cell type has
particular properties of proliferation and invasion. The placenta sustains the growth of the …

Enhancing the Robustness of Random Boolean Networks by Epigenetic Regulation

J Liu, J Dai, Q Fu, M Su, Y Luo, S Qin… - IEEE Transactions on …, 2025 - ieeexplore.ieee.org
Random Boolean Network (RBN) is a type of regulatory network in which the nodes have
Boolean values representing their states. The robustness of RBNs against perturbations is a …

Artificial biochemical networks: Evolving dynamical systems to control dynamical systems

MA Lones, LA Fuente, AP Turner… - IEEE transactions on …, 2013 - ieeexplore.ieee.org
Biological organisms exist within environments in which complex nonlinear dynamics are
ubiquitous. They are coupled to these environments via their own complex dynamical …

The artificial epigenetic network

AP Turner, MA Lones, LA Fuente… - 2013 IEEE …, 2013 - ieeexplore.ieee.org
In this paper we describe an Artificial Gene Regulatory Network (AGRN), whose form and
function are inspired by biological epigenetics. This new architecture, termed an Artificial …

The incorporation of epigenetics in artificial gene regulatory networks

AP Turner, MA Lones, LA Fuente, S Stepney… - BioSystems, 2013 - Elsevier
Artificial gene regulatory networks are computational models that draw inspiration from
biological networks of gene regulation. Since their inception they have been used to infer …

De-redundancy in a random boolean network using knockout

J Liu, J Dai, M Su, S Zhang, Y Hua, Y Wang… - Proceedings of the …, 2022 - dl.acm.org
Random Boolean Network (RBN) is one of the regulatory networks and the state value of its
node is a binary variable. The network usually contains complex interaction and redundancy …

Computational models of signalling networks for non-linear control

LA Fuente, MA Lones, AP Turner, S Stepney, LS Caves… - BioSystems, 2013 - Elsevier
Artificial signalling networks (ASNs) are a computational approach inspired by the signalling
processes inside cells that decode outside environmental information. Using evolutionary …

[HTML][HTML] Evolutionary acquisition of complex traits in artificial epigenetic networks

A Turner, A Tyrrell, M Trefzer, M Lones - Biosystems, 2019 - Elsevier
How complex traits arise within organisms over evolutionary time is an important question
that has relevance both to the understanding of biological systems and to the design of bio …

[PDF][PDF] Investigating modularity and transparency within bioinspired connectionist architectures using genetic and epigenetic models.

G Lacey - 2022 - hull-repository.worktribe.com
Abstract Machine learning algorithms allow computers to deal with incomplete data in tasks
such as speech recognition and object detection. Some machine learning algorithms take …

[PDF][PDF] Improving the Transparency of Deep Neural Networks using Artificial Epigenetic Molecules.

G Lacey, AM Schoene, N Dethlefs, AP Turner - IJCCI, 2020 - scitepress.org
Artificial gene regulatory networks (AGRNs) are connectionist architectures inspired by
biological gene regulation capable of solving tasks within complex dynamical systems. The …