Aims Debridement, antibiotics, and implant retention (DAIR) is a widely accepted form of
surgical treatment for patients with an early periprosthetic joint infection (PJI) after primary …

Introduction: The most common causative organism in periprosthetic joint infections (PJIs) is
Gram-positive bacteria that are increasingly drug resistant. In these cases the use of …

Infections associated with orthopaedic implants represent a major health concern
characterized by a remarkable incidence of morbidity and mortality. The wide variety of …

Periprosthetic joint infection (PJI) is one of the main causes for the failure of joint
arthroplasty. In view of the limited clinical effect of oral/injectable antibiotics and the drug …

Locally applied vancomycin is increasingly being used in primary hip and knee arthroplasty
to reduce the risk of infection. Despite encouraging initial results, considerable debate …

Background Periprosthetic shoulder infection (PSI) remains a devastating complication after
reverse shoulder arthroplasty (RSA). Currently, scientific data related to the management of …

Vancomycin is commonly used in outpatient parenteral antimicrobial therapy (OPAT) of
Gram-positive infections. Therapeutic drug monitoring and adverse event monitoring pose a …

The rate of eradication of periprosthetic joint infection (PJI) caused by methicillin-resistant
Staphylococcus aureus (MRSA) is still not satisfactory with systemic vancomycin …

Osteomyelitis associated with periprosthetic joint infection (PJI) signals a chronic infection
and the need for revision surgery. An osteomyelitic bone exhibits distinct morphological …

Background In severe periprosthetic joint infection after total knee arthroplasty (TKA),
multistage procedures are indicated for ongoing signs of infection after implant removal …