[HTML][HTML] Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …
The healthy human microbiome
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …
give rise to tremendous phenotypic diversity across the human population. By contrast, the …
VFDB 2022: a general classification scheme for bacterial virulence factors
B Liu, D Zheng, S Zhou, L Chen… - Nucleic acids research, 2022 - academic.oup.com
The virulence factor database (VFDB, http://www. mgc. ac. cn/VFs/) is dedicated to
presenting a comprehensive knowledge base and a versatile analysis platform for bacterial …
presenting a comprehensive knowledge base and a versatile analysis platform for bacterial …
Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …
[HTML][HTML] Gut-microbiota-targeted diets modulate human immune status
Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …
determined how two microbiota-targeted dietary interventions, plant-based fiber and …
The person-to-person transmission landscape of the gut and oral microbiomes
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …
of several health conditions,. However, the extent to which interpersonal relations shape the …
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
Preclinical mouse models suggest that the gut microbiome modulates tumor response to
checkpoint blockade immunotherapy; however, this has not been well-characterized in …
checkpoint blockade immunotherapy; however, this has not been well-characterized in …
The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients
Anti–PD-1–based immunotherapy has had a major impact on cancer treatment but has only
benefited a subset of patients. Among the variables that could contribute to interpatient …
benefited a subset of patients. Among the variables that could contribute to interpatient …
Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1
Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with
antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but …
antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but …
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Abstract Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4
and PD-1 is associated with clinical benefit across tumor types, but also a high rate of …
and PD-1 is associated with clinical benefit across tumor types, but also a high rate of …