Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is
balanced to maximise absorptive capacity, while maintaining efficient defensive reactions …

The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …

Klebsiella pneumoniae is now recognized as an urgent threat to human health because of
the emergence of multidrug-resistant strains associated with hospital outbreaks and …

Diarrheal diseases are one of the major causes of mortality among children under five years
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …

Enterotoxigenic Escherichia coli (ETEC) is one of the most common bacterial causes of
diarrhea-associated morbidity and mortality, particularly among infants and young children …

The timelines for develo** vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Every year, more than half a million children die due to diarrheal diseases. Recent studies
have identified the most important etiologies of diarrheal disease are enterotoxigenic and …

Background. Typhoid fever is a major global health problem, the control of which is hindered
by lack of a suitable animal model in which to study Salmonella Typhi infection. Until 1974, a …

Background There is no licensed vaccine against enterotoxigenic Escherichia coli (ETEC), a
major cause of diarrhea-associated morbidity and mortality among infants and children in …

Since the 18th century a wealth of knowledge regarding infectious disease pathogenesis,
prevention, and treatment has been accumulated from findings of infection challenges in …