Biomimetic design strategies for biomedical applications

X Wei, Y Wang, Y Liu, K Ji, K Li, J Wang, Z Gu - Matter, 2024‏ - cell.com
Creatures in nature adapt to changing environments by sha** their structures and
functions in ingenious ways. A major focus of current biomedical research is seeking …

Polymer-mediated protein/peptide therapeutic stabilization: current progress and future directions

RP Sivasankaran, K Snell, G Kunkel, P Georgiou… - Progress in Polymer …, 2024‏ - Elsevier
Proteins and peptides have played a pivotal role in revolutionizing disease treatment over
the last century. Despite their commercial success, protein therapeutics can be eliminated or …

Polymerization‐induced Chiral Self‐assembly for the In situ Construction, Modulation, Amplification and Applications of Asymmetric Suprastructures

X Cheng, W Zhang - Angewandte Chemie, 2024‏ - Wiley Online Library
In the polymerization‐induced chiral self‐assembly (PICSA) process, chiral functional
monomers undergo spontaneous supramolecular self‐assembly and asymmetric stacking …

[HTML][HTML] Self-Assembly of Polymers and Their Applications in the Fields of Biomedicine and Materials

L Hu, S Zhou, X Zhang, C Shi, Y Zhang, X Chen - Polymers, 2024‏ - mdpi.com
Polymer self-assembly can prepare various shapes and sizes of pores, making it widely
used. The complexity and diversity of biomolecules make them a unique class of building …

Construction of the Glycolysis Metabolic Pathway Inside an Artificial Cell for the Synthesis of Amino Acid and Its Reversible Deformation

B Yang, C Li, Y Ren, W Wang, X Zhang… - Journal of the American …, 2024‏ - ACS Publications
The bottom-up construction of artificial cells is beneficial for understanding cell working
mechanisms. The glycolysis metabolism mimicry inside artificial cells is challenging. Herein …

Morphology remodelling and membrane channel formation in synthetic cells via reconfigurable DNA nanorafts

S Fan, S Wang, L Ding, T Speck, H Yan… - Nature Materials, 2025‏ - nature.com
The shape of biological matter is central to cell function at different length scales and
determines how cellular components recognize, interact and respond to one another …

Photochemically Triggered, Transient, and Oscillatory Transcription Machineries Guide Temporal Modulation of Fibrinogenesis

J Dong, I Willner - Journal of the American Chemical Society, 2024‏ - ACS Publications
Photochemically triggered, transient, and temporally oscillatory-modulated transcription
machineries are introduced. The resulting dynamic transcription circuits are implemented to …

Intracellular Photocatalytic NADH/NAD (P) H Oxidation for Cancer Drug Development

AK Yadav, R Kushwaha, AA Mandal… - Journal of the …, 2025‏ - ACS Publications
Photocatalytic cancer therapy (PCT) has emerged as a cutting-edge anticancer mechanism
of action, harnessing light energy to mediate the catalytic oxidation of intracellular …

[HTML][HTML] Polymer vesicles as nanoreactors for biomedical applications

Z Zhang, Z Fan, J Du - Precision Medicine and Engineering, 2024‏ - Elsevier
The vesicle, which consists of the cytoplasm encapsulated by the lipid bilayer, has acted as
an important mediator of intercellular communication as a potential tool for disease …