The mechanism and role of ADAMTS protein family in osteoarthritis

T Li, J Peng, Q Li, Y Shu, P Zhu, L Hao - Biomolecules, 2022 - mdpi.com
Osteoarthritis (OA) is a principal cause of aches and disability worldwide. It is characterized
by the inflammation of the bone leading to degeneration and loss of cartilage function …

[HTML][HTML] Osteoarthritis year in review 2018: mechanics

LE DeFrate, SY Kim-Wang, ZA Englander… - Osteoarthritis and …, 2019 - Elsevier
Objective To review recent biomechanics literature focused on the interactions between
biomechanics and articular cartilage health, particularly focused on macro-scale and human …

Use of computational modeling to study joint degeneration: a review

S Mukherjee, M Nazemi, I Jonkers… - … in Bioengineering and …, 2020 - frontiersin.org
Osteoarthritis (OA), a degenerative joint disease, is the most common chronic condition of
the joints, which cannot be prevented effectively. Computational modeling of joint …

[HTML][HTML] Collagen fibres determine the crack morphology in articular cartilage

EK Moo, P Tanska, S Federico, Y Al-Saffar, W Herzog… - Acta Biomaterialia, 2021 - Elsevier
Cracks in articular cartilage compromise tissue integrity and mechanical properties and lead
to chondral lesions if untreated. An understanding of the mechanics of cracked cartilage may …

Diffusion tensor imaging of the knee to predict childhood growth

D Jaramillo, P Duong, JC Nguyen, S Mostoufi-Moab… - Radiology, 2022 - pubs.rsna.org
Background Accurate and precise methods to predict growth remain lacking. Diffusion
tensor imaging (DTI) depicts the columnar structure of the physis and metaphyseal …

T 2 orientation anisotropy map** of articular cartilage using qMRI

HPP Leskinen, NE Hänninen… - Physics in Medicine & …, 2023 - iopscience.iop.org
Objective. To provide orientation-independent MR parameters potentially sensitive to
articular cartilage degeneration by measuring isotropic and anisotropic components of T 2 …

Diffusion tractography of the rat knee at microscopic resolution

N Wang, AJ Mirando, G Cofer, Y Qi… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To evaluate whole knee joint tractography, including articular cartilage, ligaments,
meniscus, and growth plate using diffusion tensor imaging (DTI) at microscopic resolution …

A computational algorithm to simulate disorganization of collagen network in injured articular cartilage

P Tanska, P Julkunen, RK Korhonen - Biomechanics and modeling in …, 2018 - Springer
Cartilage defects are a known risk factor for osteoarthritis. Estimation of structural changes in
these defects could help us to identify high risk defects and thus to identify patients that are …

An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

SA Elahi, P Tanska, RK Korhonen, R Lories… - … in Bioengineering and …, 2021 - frontiersin.org
Injurious mechanical loading of articular cartilage and associated lesions compromise the
mechanical and structural integrity of joints and contribute to the onset and progression of …

Diffusion tensor imaging of articular cartilage using a navigated radial imaging spin-echo diffusion (RAISED) sequence

A Duarte, A Ruiz, U Ferizi, J Bencardino… - European …, 2019 - Springer
Objective To validate a radial imaging spin-echo diffusion tensor (RAISED) sequence for
high-resolution diffusion tensor imaging (DTI) of articular cartilage at 3 T. Methods The …