The central dogma decentralized: new perspectives on RNA function and local translation in neurons

CE Holt, EM Schuman - Neuron, 2013 - cell.com
The elaborate morphology of neurons together with the information processing that occurs in
remote dendritic and axonal compartments makes the use of decentralized cell biological …

Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease

IA Qureshi, MF Mehler - Nature Reviews Neuroscience, 2012 - nature.com
Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …

MicroRNAs: key regulators in the central nervous system and their implication in neurological diseases

DD Cao, L Li, WY Chan - International journal of molecular sciences, 2016 - mdpi.com
MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …

[HTML][HTML] MicroRNA loss enhances learning and memory in mice

W Konopka, A Kiryk, M Novak, M Herwerth… - Journal of …, 2010 - Soc Neuroscience
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role
in a modulation of translation of mRNA transcripts necessary for differentiation in many cell …

[HTML][HTML] MicroRNAs shape the neuronal landscape

E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …

MicroRNA networks direct neuronal development and plasticity

NFM Olde Loohuis, A Kos, GJM Martens… - Cellular and Molecular …, 2012 - Springer
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-
transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs …

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration

JA Saugstad - Journal of Cerebral Blood Flow & Metabolism, 2010 - journals.sagepub.com
MicroRNAs are small RNAs that function as regulators of posttranscriptional gene
expression. MicroRNAs are encoded by genes, and processed to form ribonucleoprotein …

MicroRNAs and synaptic plasticity—a mutual relationship

A Aksoy-Aksel, F Zampa… - … Transactions of the …, 2014 - royalsocietypublishing.org
MicroRNAs (miRNAs) are rapidly emerging as central regulators of gene expression in the
postnatal mammalian brain. Initial studies mostly focused on the function of specific miRNAs …

The miRNome of depression

D Żurawek, G Turecki - International Journal of Molecular Sciences, 2021 - mdpi.com
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …