The central dogma decentralized: new perspectives on RNA function and local translation in neurons
The elaborate morphology of neurons together with the information processing that occurs in
remote dendritic and axonal compartments makes the use of decentralized cell biological …
remote dendritic and axonal compartments makes the use of decentralized cell biological …
Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
IA Qureshi, MF Mehler - Nature Reviews Neuroscience, 2012 - nature.com
Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …
MicroRNAs: key regulators in the central nervous system and their implication in neurological diseases
MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …
[HTML][HTML] MicroRNA loss enhances learning and memory in mice
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role
in a modulation of translation of mRNA transcripts necessary for differentiation in many cell …
in a modulation of translation of mRNA transcripts necessary for differentiation in many cell …
[HTML][HTML] MicroRNAs shape the neuronal landscape
E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
MicroRNA networks direct neuronal development and plasticity
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-
transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs …
transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs …
Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review
MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …
MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration
JA Saugstad - Journal of Cerebral Blood Flow & Metabolism, 2010 - journals.sagepub.com
MicroRNAs are small RNAs that function as regulators of posttranscriptional gene
expression. MicroRNAs are encoded by genes, and processed to form ribonucleoprotein …
expression. MicroRNAs are encoded by genes, and processed to form ribonucleoprotein …
MicroRNAs and synaptic plasticity—a mutual relationship
A Aksoy-Aksel, F Zampa… - … Transactions of the …, 2014 - royalsocietypublishing.org
MicroRNAs (miRNAs) are rapidly emerging as central regulators of gene expression in the
postnatal mammalian brain. Initial studies mostly focused on the function of specific miRNAs …
postnatal mammalian brain. Initial studies mostly focused on the function of specific miRNAs …
The miRNome of depression
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …
environmental factors. It is well established that stress responses are associated with …