RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …

Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …

Summary mRNA processing, transport, translation, and ultimately degradation involve a
series of dedicated protein complexes that often assemble into large membraneless …

To understand the mechanistic role of G3BP and its partners Caprin1 and USP10 in SG
formation, we used siRNA to knockdown (KD) expression of G3BP1, G3BP2, G3BP1 and …

Dysregulation of mRNA translation is a frequent feature of neoplasia. Many oncogenes and
tumour suppressors affect the translation machinery, making aberrant translation a …

Ribonucleoprotein (RNP) granules are RNA–protein assemblies that are involved in
multiple aspects of RNA metabolism and are linked to memory, development, and disease …

Stress granules are condensates of non-translating mRNAs and proteins involved in the
stress response and neurodegenerative diseases. Stress granules form in part through …

Stress granules (SGs) contain translationally-stalled mRNAs, associated preinitiation factors,
and specific RNA-binding proteins. In addition, many signaling proteins are recruited to SGs …

Preventing the immune escape of tumor cells by blocking inhibitory checkpoints, such as the
interaction between programmed death ligand-1 (PD-L1) and programmed death-1 (PD-1) …

Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize
post-transcriptional control mechanisms to re-program gene expression in ways that …