Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Recent advances in the field of nanotechnology applications in nuclear medicine offer the
promise of better diagnostic and therapeutic options. In recent years, increasing efforts have …

Radiolabeled peptides for tumor imaging with PET that can be produced with kits are
currently in the spotlight of radiopharmacy and nuclear medicine. The diagnosis of …

The excesses of reagents used in protein chemistry are often incompatible with the reduced
or even inverse stoichiometries used for efficient radiolabeling. Analysis and screening of …

Unorthodox 18F-labeling strategies not employing the formation of a carbon-18F bond are
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …

18F-Labeling methods for the preparation of 18F-labeled molecular probes can be classified
into electrophilic fluorination, nucleophilic fluorination, metal-F coordination, and 18F/19F …

The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules,
such as peptides, proteins and biologically relevant small molecules, has improved the …

Owing to their large size proteinaceous drugs offer higher operative information content
compared to the small molecules that correspond to the traditional understanding of …

Here we present a procedure to label peptides with the positron-emitting radioisotope
fluorine-18 (18 F) using the silicon-fluoride acceptor (SiFA) labeling methodology. Positron …

The clinical applications of positron emission tomography (PET) imaging pharmaceuticals
have increased tremendously over the past several years since the approval of 18fluorine …