Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Hydrogen sulfide (H2S) is a unique gasotransmitter, with regulatory roles in the
cardiovascular, nervous, and immune systems. Some of the vascular actions of H2S …

Hydrogen sulfide (H 2 S) is the most recent endogenous gasotransmitter that has been
reported to serve many physiological and pathological functions in different tissues. Studies …

Abstract Significance: Hydrogen sulfide (H2S) has been recognized as a signaling molecule
as well as a cytoprotectant. It modulates neurotransmission, regulates vascular tone, and …

Significance: An abundance of experimental evidence suggests that hydrogen sulfide (H2S)
plays a prominent role in physiology and pathophysiology. Many targets exist for H2S …

The enzymes of the transsulfuration pathway, cystathionine β-synthase (CBS) and
cystathionine γ-lyase (CSE), are important for the endogenous production of hydrogen …

Nitric oxide (NO) vascular signaling has long been considered an independent, self-
sufficient pathway. However, recent data indicate that the novel gaseous mediator, hydrogen …

For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H2S as an endogenous signaling …

Hydrogen sulfide (H 2 S) is an endogenous gasotransmitter with physiologic functions
similar to nitric oxide and carbon monoxide. Exogenous treatment with H 2 S can induce a …