Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

L Zhu, M Luo, Y Zhang, F Fang, M Li, F An… - Coordination chemistry …, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

Engineering nanosystems to overcome barriers to cancer diagnosis and treatment

SO Alhaj-Suliman, EI Wafa, AK Salem - Advanced drug delivery reviews, 2022 - Elsevier
Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Reactive X (where X= O, N, S, C, Cl, Br, and I) species nanomedicine

K Wang, W Mao, X Song, M Chen, W Feng… - Chemical Society …, 2023 - pubs.rsc.org
Reactive oxygen, nitrogen, sulfur, carbonyl, chlorine, bromine, and iodine species (RXS,
where X= O, N, S, C, Cl, Br, and I) have important roles in various normal physiological …

Reactive oxygen nano-generators for cancer therapy

D Kalyane, D Choudhary, S Polaka, H Goykar… - Progress in Materials …, 2022 - Elsevier
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Engineering nanoparticles to reprogram radiotherapy and immunotherapy: recent advances and future challenges

J **, Q Zhao - Journal of nanobiotechnology, 2020 - Springer
Nanoparticles (NPs) have been increasingly studied for radiosensitization. The principle of
NPs radio-enhancement is to use high-atomic number NPs (eg gold, hafnium, bismuth and …

Polyelectrolyte multilayers assembled entirely from immune signals on gold nanoparticle templates promote antigen-specific T cell response

P Zhang, YC Chiu, LH Tostanoski, CM Jewell - Acs Nano, 2015 - ACS Publications
Materials that allow modular, defined assembly of immune signals could support a new
generation of rationally designed vaccines that promote tunable immune responses. Toward …

Cisplatin-tethered gold nanospheres for multimodal chemo-radiotherapy of glioblastoma

S Setua, M Ouberai, SG Piccirillo, C Watts, M Welland - Nanoscale, 2014 - pubs.rsc.org
Glioblastoma multiforme (GBM) remains the most aggressive and challenging brain tumour
to treat. We report the first successful chemo-radiotherapy on patient derived treatment …

New frontiers in molecular imaging with superparamagnetic iron oxide nanoparticles (SPIONs): efficacy, toxicity, and future applications

V Frantellizzi, M Conte, M Pontico, A Pani… - Nuclear medicine and …, 2020 - Springer
Abstract Supermagnetic Iron Oxide Nanoparticles (SPIONs) are nanoparticles that have an
iron oxide core and a functionalized shell. SPIONs have recently raised much interest in the …