Classic models for dynamic contrast‐enhanced MRI

SP Sourbron, DL Buckley - NMR in Biomedicine, 2013 - Wiley Online Library
Dynamic contrast‐enhanced MRI (DCE‐MRI) is a functional MRI method where T1‐
weighted MR images are acquired dynamically after bolus injection of a contrast agent. The …

Models and methods for analyzing DCE‐MRI: A review

F Khalifa, A Soliman, A El‐Baz… - Medical …, 2014 - Wiley Online Library
Purpose: To present a review of most commonly used techniques to analyze dynamic
contrast‐enhanced magnetic resonance imaging (DCE‐MRI), discusses their strengths and …

[HTML][HTML] Assessment of blood–brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review

AK Heye, RD Culling, MCV Hernández… - NeuroImage: Clinical, 2014 - Elsevier
There is increasing recognition of the importance of blood–brain barrier (BBB) disruption in
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …

[HTML][HTML] Quantifying blood-brain barrier leakage in small vessel disease: review and consensus recommendations

MJ Thrippleton, WH Backes, S Sourbron… - Alzheimer's & …, 2019 - Elsevier
Cerebral small vessel disease (cSVD) comprises pathological processes of the small
vessels in the brain that may manifest clinically as stroke, cognitive impairment, dementia, or …

[HTML][HTML] Perfusion and vascular permeability: basic concepts and measurement in DCE-CT and DCE-MRI

CA Cuenod, D Balvay - Diagnostic and interventional imaging, 2013 - Elsevier
The microvascular network formed by the capillaries supplies the tissues and permits their
function. It provides a considerable surface area for exchanges between blood and tissues …

Extra-Virgin Olive Oil Enhances the Blood–Brain Barrier Function in Mild Cognitive Impairment: A Randomized Controlled Trial

A Kaddoumi, TS Denney Jr, G Deshpande… - Nutrients, 2022 - mdpi.com
Mild cognitive impairment (MCI) and early Alzheimer's disease (AD) are characterized by
blood–brain barrier (BBB) breakdown leading to abnormal BBB permeability ahead of brain …

CT perfusion of the liver: principles and applications in oncology

SH Kim, A Kamaya, JK Willmann - Radiology, 2014 - pubs.rsna.org
With the introduction of molecularly targeted chemotherapeutics, there is an increasing need
for defining new response criteria for therapeutic success because use of morphologic …

[HTML][HTML] Tracer kinetic modelling for DCE-MRI quantification of subtle blood–brain barrier permeability

AK Heye, MJ Thrippleton, PA Armitage… - Neuroimage, 2016 - Elsevier
There is evidence that subtle breakdown of the blood–brain barrier (BBB) is a
pathophysiological component of several diseases, including cerebral small vessel disease …

Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge

W Huang, X Li, Y Chen, X Li, MC Chang… - Translational …, 2014 - Elsevier
Pharmacokinetic analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-
MRI) time-course data allows estimation of quantitative parameters such as K trans (rate …

Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success

BW Pogue, JT Elliott, SC Kanick… - Physics in Medicine …, 2016 - iopscience.iop.org
Photodynamic therapy (PDT) can be a highly complex treatment, with many parameters
influencing treatment efficacy. The extent to which dosimetry is used to monitor and …