Deep multiple instance learning on heterogeneous graph for drug–disease association prediction
Drug repositioning offers promising prospects for accelerating drug discovery by identifying
potential drug–disease associations (DDAs) for existing drugs and diseases. Previous …
potential drug–disease associations (DDAs) for existing drugs and diseases. Previous …
[HTML][HTML] MGACL: Prediction Drug–Protein Interaction Based on Meta-Graph Association-Aware Contrastive Learning
P Zhang, P Lin, D Li, W Wang, X Qi, J Li, J **ong - Biomolecules, 2024 - mdpi.com
The identification of drug–target interaction (DTI) is crucial for drug discovery. However, how
to reduce the graph neural network's false positives due to its bias and negative transfer in …
to reduce the graph neural network's false positives due to its bias and negative transfer in …
OSGAN: Omni-scale and Global-aware ECG arrhythmia diagnostic network
Automated arrhythmia detection using electrocardiogram (ECG) signals is critical for
cardiovascular disease prevention and treatment. However, the widely used CNN-based …
cardiovascular disease prevention and treatment. However, the widely used CNN-based …
Drug repositioning based on tripartite cross-network embedding and graph convolutional network
Drug-disease association prediction is an important part of drug discovery, which can help
researchers uncover potential drug candidates and disease targets more accurately to deal …
researchers uncover potential drug candidates and disease targets more accurately to deal …
SGCLDGA: unveiling drug–gene associations through simple graph contrastive learning
Y Fan, C Zhang, X Hu, Z Huang, J Xue… - Briefings in …, 2024 - academic.oup.com
Drug repurposing offers a viable strategy for discovering new drugs and therapeutic targets
through the analysis of drug–gene interactions. However, traditional experimental methods …
through the analysis of drug–gene interactions. However, traditional experimental methods …
SDDSynergy: Learning Important Molecular Substructures for Explainable Anticancer Drug Synergy Prediction
Drug combination therapies are well-established strategies for the treatment of cancer with
low toxicity and fewer adverse effects. Computational drug synergy prediction approaches …
low toxicity and fewer adverse effects. Computational drug synergy prediction approaches …
AGCLNDA: Enhancing the Prediction of ncRNA-Drug Resistance Association Using Adaptive Graph Contrastive Learning
Y Fan, C Zhang, X Hu, Z Huang… - IEEE Journal of …, 2025 - ieeexplore.ieee.org
Non-coding RNAs (ncRNAs), which do not encode proteins, have been implicated in
chemotherapy resistance in cancer treatment. Given the high costs and time requirements of …
chemotherapy resistance in cancer treatment. Given the high costs and time requirements of …
Boosting drug-disease association prediction for drug repositioning via dual-feature extraction and cross-dual-domain decoding
The extraction of biomedical data has significant academic and practical value in
contemporary biomedical sciences. In recent years, drug repositioning, a cost-effective …
contemporary biomedical sciences. In recent years, drug repositioning, a cost-effective …
Key Substructure Learning with Chemical Intuition for Material Property Prediction
Substructures are crucial factors influencing material molecular properties, and the effective
identification of molecular substructures can accelerate novel material discovery. The …
identification of molecular substructures can accelerate novel material discovery. The …
Antibiotic Bacteria Interaction: Dataset and Benchmarking.
This study introduces a dataset for drug-bacteria associations (DBA) that affects humans.
Our contribution extends beyond merely curating the association matrix; we also conduct …
Our contribution extends beyond merely curating the association matrix; we also conduct …