A comprehensive review of non-steroidal anti-inflammatory drug use in the elderly

S Wongrakpanich, A Wongrakpanich… - Aging and …, 2018 - pmc.ncbi.nlm.nih.gov
NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed
pain medications. It is a highly effective drug class for pain and inflammation; however …

[HTML][HTML] Inflammation and stroke risk: a new target for prevention

PJ Kelly, R Lemmens, G Tsivgoulis - Stroke, 2021 - journals.lww.com
New therapeutic approaches are required for secondary prevention of residual vascular risk
after stroke. Diverse sources of evidence support a causal role for inflammation in the …

Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice

C Park, O Hahn, S Gupta, AJ Moreno, F Marino, B Kedir… - Nature aging, 2023 - nature.com
Platelet factors regulate wound healing and can signal from the blood to the brain,.
However, whether platelet factors modulate cognition, a highly valued and central …

Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19

MM Rogero, MC Leao, TM Santana… - Free radical biology and …, 2020 - Elsevier
Studies have shown that infection, excessive coagulation, cytokine storm, leukopenia,
lymphopenia, hypoxemia and oxidative stress have also been observed in critically ill …

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
Atherosclerosis is an inflammatory disease within the arterial wall that is responsible for
several important adverse vascular events, including coronary artery disease, myocardial …

Matrix metalloproteinases in myocardial infarction and heart failure

KY DeLeon-Pennell, CA Meschiari, M Jung… - Progress in molecular …, 2017 - Elsevier
Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

PM Rothwell, M Wilson, CE Elwin, B Norrving, A Algra… - The Lancet, 2010 - thelancet.com
Background High-dose aspirin (≥ 500 mg daily) reduces long-term incidence of colorectal
cancer, but adverse effects might limit its potential for long-term prevention. The long-term …

Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments

JL Mega, T Simon - The Lancet, 2015 - thelancet.com
Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, prevent and
treat many cardiovascular disorders and, as such, are some of the most commonly …