Infectious disease risk across the growing human-non human primate interface: a review of the evidence
Most of the human pandemics reported to date can be classified as zoonoses. Among these,
there is a long history of infectious diseases that have spread from non-human primates …
there is a long history of infectious diseases that have spread from non-human primates …
Advancing the understanding of treponemal disease in the past and present
Syphilis was perceived to be a new disease in Europe in the late 15th century, igniting a
debate about its origin that continues today in anthropological, historical, and medical …
debate about its origin that continues today in anthropological, historical, and medical …
Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons
EF Sørensen, RA Harris, L Zhang, M Raveendran… - Science, 2023 - science.org
Baboons (genus Papio) are a morphologically and behaviorally diverse clade of catarrhine
monkeys that have experienced hybridization between phenotypically and genetically …
monkeys that have experienced hybridization between phenotypically and genetically …
Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages
MA Beale, M Marks, SK Sahi, LC Tantalo… - Nature …, 2019 - nature.com
Syphilis is a sexually transmitted infection caused by Treponema pallidum subspecies
pallidum and may lead to severe complications. Recent years have seen striking increases …
pallidum and may lead to severe complications. Recent years have seen striking increases …
A treponemal genome from an historic plague victim supports a recent emergence of yaws and its presence in 15th century Europe
Developments in techniques for identification of pathogen DNA in archaeological samples
can expand our resolution of disease detection. Our application of a non-targeted molecular …
can expand our resolution of disease detection. Our application of a non-targeted molecular …
Clonal isolates of Treponema pallidum subsp. pallidum Nichols provide evidence for the occurrence of microevolution during experimental rabbit infection and in vitro …
DG Edmondson, BD De Lay, BM Hanson, LE Kowis… - PLoS …, 2023 - journals.plos.org
The recent development of a system for long-term in vitro culture of the syphilis spirochete,
Treponema pallidum subsp. pallidum, has introduced the possibility of detailed genetic …
Treponema pallidum subsp. pallidum, has introduced the possibility of detailed genetic …
[HTML][HTML] Neglected tropical diseases: elimination and eradication
C Bodimeade, M Marks, D Mabey - Clinical Medicine, 2019 - Elsevier
The term neglected tropical diseases (NTDs) describes a disparate group of diseases which
affect populations living in poverty and are important causes of morbidity and mortality …
affect populations living in poverty and are important causes of morbidity and mortality …
Directly sequenced genomes of contemporary strains of syphilis reveal recombination-driven diversity in genes encoding predicted surface-exposed antigens
Syphilis, caused by Treponema pallidum subsp. pallidum (TPA), remains an important
public health problem with an increasing worldwide prevalence. Despite recent advances in …
public health problem with an increasing worldwide prevalence. Despite recent advances in …
Genetics of human and animal uncultivable treponemal pathogens
D Šmajs, M Strouhal, S Knauf - Infection, Genetics and Evolution, 2018 - Elsevier
Treponema pallidum is an uncultivable bacterium and the causative agent of syphilis
(subsp. pallidum [TPA]), human yaws (subsp. pertenue [TPE]), and bejel (subsp …
(subsp. pallidum [TPA]), human yaws (subsp. pertenue [TPE]), and bejel (subsp …
Comparison of target enrichment strategies for ancient pathogen DNA
A Furtwängler, J Neukamm, L Böhme, E Reiter… - …, 2020 - Taylor & Francis
In ancient DNA research, the degraded nature of the samples generally results in poor
yields of highly fragmented DNA; targeted DNA enrichment is thus required to maximize …
yields of highly fragmented DNA; targeted DNA enrichment is thus required to maximize …