The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …

Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …

Organoid culture systems have emerged as a frontier technology in liver and biliary
research. These three‐dimensional (3D) cell cultures derived from pluripotent and adult …

The human endometrium is a highly regenerative tissue capable of undergoing scarless
repair during the menstruation and postpartum phases. This process is mediated by …

Dogs develop complex multifactorial diseases analogous to humans, including inflammatory
diseases, metabolic diseases, and cancer. Therefore, they represent relevant large animal …

Animal organoid models derived from farm and companion animals have great potential to
contribute to human health as a One Health initiative, which recognize a close inter …

Preclinical biomedical research is limited by the predictiveness of in vivo and in vitro models.
While in vivo models offer the most complex system for experimentation, they are also …

The liver is the most important metabolic organ in the body. While mouse models and cell
lines have further deepened our understanding of liver biology and related diseases, they …

Organoid technology is a state‐of‐the‐art cell culture tool that has revolutionized study of
development, regeneration, and diseases. Human liver organoids (HLOs) are now derived …