In multicellular organisms, Wnt proteins govern stem and progenitor cell renewal and
differentiation to regulate embryonic development, adult tissue homeostasis and tissue …

Within embryonic development, the occurrence of gastrulation is critical in the formation of
multiple germ layers with many differentiative abilities. These cells are instructed through …

Understanding how cells communicated before the evolution of nervous systems in early
metazoans is key to unraveling the origins of multicellular life. We focused on Trichoplax …

Filopodia, widely distributed on cell surfaces, are distinguished by their dynamic extensions,
playing pivotal roles in a myriad of biological processes. Their functions span from …

Cellular communication through the dissemination of signal molecules is vital for tissue
organisation and homeostasis. The mechanisms of signal spreading can include binding …

Extracellular vesicles (EVs) are membrane vesicles originating from different cells within the
brain. The pathophysiological role of EVs in neurodegenerative diseases is progressively …

Wnt signalling is an essential signalling system in neurogenesis, with a crucial role in
synaptic plasticity and neuronal survival, processes that are disrupted in Alzheimer's …

The blood–brain barrier (BBB) is a complex structure that separates the central nervous
system (CNS) from the peripheral blood circulation. Effective communication between …

The Wnt signaling pathway is a huge network governing development and homeostasis,
dysregulation of which is associated with a myriad of human diseases. The Frizzled receptor …

Zebrafish (Danio rerio) has ascended as a pivotal model organism in the realm of gut-brain
axis research, principally owing to its high-throughput experimental capabilities and …