Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

Bacterial biofilms are communities of cells enclosed in an extracellular polymeric matrix in
which cells adhere to each other and to foreign surfaces. The development of a biofilm is a …

How do growing bacterial colonies get their shapes? While colony morphogenesis is well
studied in two dimensions, many bacteria grow as large colonies in three-dimensional (3D) …

Bacterial biofilms represent a basic form of multicellular organization that confers survival
advantages to constituent cells. The sequential stages of cell ordering during biofilm …

During development, organisms acquire three-dimensional (3D) shapes with important
physiological consequences. While basic mechanisms underlying morphogenesis are …

Pel exopolysaccharide biosynthetic loci are phylogenetically widespread biofilm matrix
determinants in bacteria. In Pseudomonas aeruginosa, Pel is crucial for cell-to-cell …

Modern molecular microbiology elucidates the organizational principles of bacterial biofilms
via detailed examination of the interplay between signaling and gene regulation. A …

Self-organized multicellular behaviors enable cells to adapt and tolerate stressors to a
greater degree than isolated cells. However, whether and how cellular communities alter …

Collective migration—the directed, coordinated motion of many self-propelled agents—is a
fascinating emergent behavior exhibited by active matter with functional implications for …

The emergence of spatial organisation in biofilm growth is one of the most fundamental
topics in biofilm biophysics and microbiology. It has long been known that growing biofilms …