The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …

This review synthesizes relations between mindfulness and resting-state fMRI functional
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …

Background: Emotional disorders are common comorbid affectations that exacerbate the
severity and persistence of chronic pain. Specifically, depressive symptoms can lead to an …

Recently, clinicians have been using repetitive transcranial magnetic stimulation (rTMS) for
treating various pain conditions. This systematic narrative review aimed to examine the use …

Essential oils (EOs) have been traditionally used as ancient remedies to treat many health
disorders due to their enormous biological activities. As mainstream allopathic medication …

This study aimed to examine the effects of luteolin (LUT) on chronic neuropathic pain (NP)-
induced mood disorders (ie, anxiety and depression) by regulating oxidative stress …

The relationship between pain and depression is thought to be bidirectional and the
underlying neurobiology 'shared'between the two conditions. However, these claims are …

The incidence of chronic pain is high in the general population and it is closely related to
anxiety disorders, which promote negative effects on the quality of life. The cannabinoid …

The autonomic nervous system (ANS) is a diffuse network that regulates physiological
systems to maintain body homeostasis by integrating inputs from the internal and external …

In this study, we aimed to evaluate the anti-inflammatory and anti-apoptotic effects of
melatonin (MLT) on neuropathic pain (NP)-induced anxiety and depression in a rat model …