Tumor microenvironment of hepatocellular carcinoma: challenges and opportunities for new treatment options
The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Inflammatory cytokines in the pathogenesis of cardiovascular disease and cancer
Inflammatory cytokines are highly inducible small glycoproteins or regulatory proteins of low
molecular weight secreted by different cell types. They regulate intercellular communication …
molecular weight secreted by different cell types. They regulate intercellular communication …
Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases
Critical cancer pathways often cannot be targeted because of limited efficiency crossing cell
membranes. Here we report the development of a Salmonella-based intracellular delivery …
membranes. Here we report the development of a Salmonella-based intracellular delivery …
Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …
Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer.
Transforming growth factor beta (TGF-β) is highly expressed in the liver tumor …
Transforming growth factor beta (TGF-β) is highly expressed in the liver tumor …
Antioxidant role of kaempferol in prevention of hepatocellular carcinoma
N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …
with the body's defense mechanism. These species also cause mutations and uncontrolled …
Radiation-induced liver disease: current understanding and future perspectives
J Kim, Y Jung - Experimental & molecular medicine, 2017 - nature.com
Although radiotherapy (RT) is used for the treatment of cancers, including liver cancer,
radiation-induced liver disease (RILD) has emerged as a major limitation of RT. Radiation …
radiation-induced liver disease (RILD) has emerged as a major limitation of RT. Radiation …
Radiomics on gadoxetic acid–enhanced magnetic resonance imaging for prediction of postoperative early and late recurrence of single hepatocellular carcinoma
S Kim, J Shin, DY Kim, GH Choi, MJ Kim, JY Choi - Clinical Cancer Research, 2019 - AACR
Purpose: To evaluate the usefulness of the radiomic model in predicting early (≤ 2 years)
and late (> 2 years) recurrence after curative resection in cases involving a single …
and late (> 2 years) recurrence after curative resection in cases involving a single …
Viral oncology: molecular biology and pathogenesis
UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …
the world's population harbors at least one of these oncoviruses, but only a small proportion …
Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma
Objectives Yttrium-90 (Y90)-radioembolisation (RE) significantly regresses locally advanced
hepatocellular carcinoma and delays disease progression. The current study is designed to …
hepatocellular carcinoma and delays disease progression. The current study is designed to …