The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

M Malone, T Bjarnsholt, AJ McBain… - Journal of wound …, 2017 - magonlinelibrary.com
The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …

Biofilm-innate immune interface: contribution to chronic wound formation

Z Versey, WS da Cruz Nizer, E Russell, S Zigic… - Frontiers in …, 2021 - frontiersin.org
Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

The role of bacterial biofilms in chronic infections

T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds

G Schultz, T Bjarnsholt, GA James… - Wound Repair and …, 2017 - Wiley Online Library
Background: Despite a growing consensus that biofilms contribute to a delay in the healing
of chronic wounds, conflicting evidence pertaining to their identification and management …

Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds

EK White, A Uberoi, JTC Pan, JT Ort, AE Campbell… - Science …, 2024 - science.org
Chronic wounds are a common and costly complication of diabetes, where multifactorial
defects contribute to dysregulated skin repair, inflammation, tissue damage, and infection …

A review of the scientific evidence for biofilms in wounds

SL Percival, KE Hill, DW Williams… - Wound repair and …, 2012 - Wiley Online Library
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the
innate barrier function of the skin and dermal appendages, facilitating the development of …

Prevention and treatment of Staphylococcus aureus biofilms

M Bhattacharya, DJ Wozniak, P Stoodley… - Expert review of anti …, 2015 - Taylor & Francis
S. aureus colonizes both artificial and tissue surfaces in humans causing chronic persistent
infections that are difficult to cure. It is a notorious pathogen due to its antibiotic recalcitrance …

Fluorescence in situ hybridization (FISH) in the microbiological diagnostic routine laboratory: a review

H Frickmann, AE Zautner, A Moter… - Critical reviews in …, 2017 - Taylor & Francis
Early identification of microbial pathogens is essential for rational and conservative antibiotic
use especially in the case of known regional resistance patterns. Here, we describe …

Biofilms in chronic infections–a matter of opportunity–monospecies biofilms in multispecies infections

M Burmølle, TR Thomsen, M Fazli, I Dige… - FEMS Immunology & …, 2010 - academic.oup.com
It has become evident that aggregation or biofilm formation is an important survival
mechanism for bacteria in almost any environment. In this review, we summarize recent …

Biofilm research in bovine mastitis

RR Pedersen, V Krömker, T Bjarnsholt… - Frontiers in veterinary …, 2021 - frontiersin.org
Bovine mastitis is one of the most important diseases in the dairy industry and has
detrimental impact on the economy and welfare of the animals. Further, treatment failure …