The brain contains a fairly low amount of glycogen, mostly located in astrocytes, a fact that
has prompted the suggestion that glycogen does not have a significant physiological role in …

Background This narrative review aims to discuss several common neurological and
psychiatric disorders that show comorbidity with migraine. Not only can we gain …

The functions of sleep and its links with neuropsychiatric diseases have long been
questioned. Among the numerous hypotheses on sleep function, early studies proposed that …

Over the last thirty years, a growing number of studies showed that astrocytes play a pivotal
role in the energy support to synapses. More precisely, astrocytes adjust energy production …

Objective Glycogen in astrocyte processes contributes to maintenance of low extracellular
glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a …

This paper reviews the role played by glycogen breakdown (glycogenolysis) and glycogen
re-synthesis in memory processing in two different chick brain regions,(1) the hippocampus …

Sleep is a naturally occurring physiological state that is required to sustain physical and
mental health. Traditionally viewed as strictly regulated by top-down control mechanisms …

Abstract In 1995 Benington and Heller formulated an energy hypothesis of sleep centered
on a key role of glycogen. It was postulated that a major function of sleep is to replenish …

Astrocytic glycogen represents the only form of glucose storage in the brain, and one of the
outcomes of its breakdown is the production of lactate that can be used by neurons as an …

Fasting or skip** meals are well-characterized migraine triggers. However, mechanisms
of the fasting-induced migraine headache are unclear. Here, we review the recent …