Pharmacogenomics in practice: A review and implementation guide

D Kabbani, R Akika, A Wahid, AK Daly… - Frontiers in …, 2023 - frontiersin.org
Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …

Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice

A Squassina, M Manchia, VG Manolopoulos… - …, 2010 - Taylor & Francis
The implementation of genetic data for a better prediction of response to medications and
adverse drug reactions is becoming a reality in some clinical fields. However, to be …

Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey

EJ Stanek, CL Sanders, KAJ Taber… - Clinical …, 2012 - Wiley Online Library
To develop a benchmark measure of US physicians' level of knowledge and extent of use of
pharmacogenomic testing, we conducted an anonymous, cross‐sectional, fax‐based …

Pharmacogenomic knowledge gaps and educational resource needs among physicians in selected specialties

KA Johansen Taber, BD Dickinson - … and personalized medicine, 2014 - Taylor & Francis
Background The use of pharmacogenomic testing in the clinical setting has the potential to
improve the safety and effectiveness of drug therapy, yet studies have revealed that …

Can pharmacogenetics help rescue drugs withdrawn from the market?

RR Shah - Pharmacogenomics, 2006 - Taylor & Francis
Observations over the later half of the last century have suggested that genetic factors may
be the prime determinant of drug response, at least for some drugs. Retrospectively …

Pharmacogenomics in clinical trials: an overview

R Nogueiras-Álvarez - Frontiers in Pharmacology, 2023 - frontiersin.org
With the trend towards promoting personalised medicine (PM), the application of
pharmacogenetics and pharmacogenomics (PGx) is of growing importance. For the …

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey

N Karas Kuželički, I Prodan Žitnik, D Gurwitz… - …, 2019 - Taylor & Francis
Aim: The need for pharmacogenomic education is becoming more and more urgent. Our aim
was to evaluate the progress in pharmacogenomics education since then, and to put forward …

Balancing personalized medicine and personalized care

K Cornetta, CG Brown - Academic Medicine, 2013 - journals.lww.com
The current description of personalized medicine by the National Institutes of Health is “the
science of individualized prevention and therapy.” Although physicians are beginning to see …

Knowledge and attitudes of medical and pharmacy students about pharmacogenomics: a systematic review and meta-analysis

C Li, X Su, Q Sun, Y Huang - The Pharmacogenomics Journal, 2023 - nature.com
Pharmacogenomics (PGx) is rapidly growing branch of molecular genetics with high
potentials to influence therapeutics. This review evaluates knowledge and attitudes of …

Cost-effectiveness of pharmacogenomics in clinical practice: a case study of thiopurine methyltransferase genoty** in acute lymphoblastic leukemia in Europe

ME van den Akker-van Marle, D Gurwitz… - …, 2006 - Taylor & Francis
Only a few studies have addressed the cost-effectiveness of pharmacogenetics interventions
in healthcare. Lack of health economics data on aspects of pharmacogenetics is perceived …