Advances in biomaterials for drug delivery
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …
Encapsulation, protection, and delivery of bioactive proteins and peptides using nanoparticle and microparticle systems: A review
DJ McClements - Advances in colloid and interface science, 2018 - Elsevier
There are many examples of bioactive proteins and peptides that would benefit from oral
delivery through functional foods, supplements, or medical foods, including hormones …
delivery through functional foods, supplements, or medical foods, including hormones …
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in
DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to …
DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to …
ConSurf: using evolutionary data to raise testable hypotheses about protein function
Many mutations disappear from the population because they impair protein function and/or
stability. Thus, amino acid positions that are essential for proper function evolve more slowly …
stability. Thus, amino acid positions that are essential for proper function evolve more slowly …
ConSurf‐DB: An accessible repository for the evolutionary conservation patterns of the majority of PDB proteins
Patterns observed by examining the evolutionary relationships among proteins of common
origin can reveal the structural and functional importance of specific residue positions. In …
origin can reveal the structural and functional importance of specific residue positions. In …
Machine learning solutions for predicting protein–protein interactions
Proteins are “social molecules.” Recent experimental evidence supports the notion that
large protein aggregates, known as biomolecular condensates, affect structurally and …
large protein aggregates, known as biomolecular condensates, affect structurally and …
Dynamic protein and polypeptide hydrogels based on Schiff base co-assembly for biomedicine
Stimuli-responsive biopolymer hydrogels are promising building blocks for biomedical
devices, attributable to their excellent hydrophilicity, biocompatibility, and dynamic …
devices, attributable to their excellent hydrophilicity, biocompatibility, and dynamic …
Nanoparticles surface chemistry influence on protein corona composition and inflammatory responses
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery,
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …
Thermoresponsive polymers: from natural proteins to amino acid based Polymer synthesis
M Badreldin, P Salas-Ambrosio, E Garanger… - Progress in Polymer …, 2023 - Elsevier
In polymer science, thermoresponsiveness refers to macromolecular systems that display a
marked and discontinuous change in their physical properties with temperature. Such smart …
marked and discontinuous change in their physical properties with temperature. Such smart …
[HTML][HTML] Are protein language models the new universal key?
Protein language models (pLMs) capture some aspects of the grammar of the language of
life as written in protein sequences. The so-called pLM embeddings implicitly contain this …
life as written in protein sequences. The so-called pLM embeddings implicitly contain this …