Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Encapsulation, protection, and delivery of bioactive proteins and peptides using nanoparticle and microparticle systems: A review

DJ McClements - Advances in colloid and interface science, 2018 - Elsevier
There are many examples of bioactive proteins and peptides that would benefit from oral
delivery through functional foods, supplements, or medical foods, including hormones …

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

H Ashkenazy, S Abadi, E Martz, O Chay… - Nucleic acids …, 2016 - academic.oup.com
The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in
DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to …

ConSurf: using evolutionary data to raise testable hypotheses about protein function

G Celniker, G Nimrod, H Ashkenazy… - Israel Journal of …, 2013 - Wiley Online Library
Many mutations disappear from the population because they impair protein function and/or
stability. Thus, amino acid positions that are essential for proper function evolve more slowly …

ConSurf‐DB: An accessible repository for the evolutionary conservation patterns of the majority of PDB proteins

A Ben Chorin, G Masrati, A Kessel, A Narunsky… - Protein …, 2020 - Wiley Online Library
Patterns observed by examining the evolutionary relationships among proteins of common
origin can reveal the structural and functional importance of specific residue positions. In …

Machine learning solutions for predicting protein–protein interactions

R Casadio, PL Martelli… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Proteins are “social molecules.” Recent experimental evidence supports the notion that
large protein aggregates, known as biomolecular condensates, affect structurally and …

Dynamic protein and polypeptide hydrogels based on Schiff base co-assembly for biomedicine

K Sahajpal, S Shekhar, A Kumar, B Sharma… - Journal of Materials …, 2022 - pubs.rsc.org
Stimuli-responsive biopolymer hydrogels are promising building blocks for biomedical
devices, attributable to their excellent hydrophilicity, biocompatibility, and dynamic …

Nanoparticles surface chemistry influence on protein corona composition and inflammatory responses

LE González-García, MN MacGregor, RM Visalakshan… - Nanomaterials, 2022 - mdpi.com
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery,
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …

Thermoresponsive polymers: from natural proteins to amino acid based Polymer synthesis

M Badreldin, P Salas-Ambrosio, E Garanger… - Progress in Polymer …, 2023 - Elsevier
In polymer science, thermoresponsiveness refers to macromolecular systems that display a
marked and discontinuous change in their physical properties with temperature. Such smart …

[HTML][HTML] Are protein language models the new universal key?

K Weissenow, B Rost - Current Opinion in Structural Biology, 2025 - Elsevier
Protein language models (pLMs) capture some aspects of the grammar of the language of
life as written in protein sequences. The so-called pLM embeddings implicitly contain this …