Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …

T cell recognition of antigen-presenting cells depends on their expression of a spectrum of
peptides bound to major histocompatibility complex class I (MHC-I) and class II (MHC-II) …

Leprosy is best understood as two conjoined diseases. The first is a chronic mycobacterial
infection that elicits an extraordinary range of cellular immune responses in humans. The …

The ability of bacteriophages to kill bacteria is well known, as is their potential use as
alternatives to antibiotics. As such, bacteriophages reach high doses locally through …

Dendritic cells constitutively sample the tissue microenvironment and phagocytose both
microbial and host apoptotic cells,,,. This leads to the induction of immunity against invading …

Psoriasis is a chronic skin disease that affects about 1.5% of the Caucasian population and
is characterized by typical macroscopic and microscopic skin alterations. Psoriatic lesions …

Abstract Concepts of cell-cell interactions in adaptive immunity have alternated between the
simple and the complex. The notion that one population of small, circulating lymphocytes is …

Heterogeneous intracellular pathways and biochemical mechanisms are responsible for
generating the glycoprotein complexes of peptide and major histocompatibility complex that …

Ionizing radiation therapy (RT) is an important local modality for the treatment of cancer. The
current rationale for its use is based largely on the ability of RT to kill the cancer cells by a …

Major histocompatibility complex class II (MHC‐II) molecules sample peptides from the
extracellular space, allowing the immune system to detect the presence of foreign microbes …