Understanding the performance of the left ventricle (LV) requires not only examining the
properties of the LV itself, but also investigating the modulating effects of the arterial system …

The aortic valve regulates unidirectional flow of oxygenated blood to the myocardium and
arterial system. The natural anatomical geometry and microstructural complexity ensures …

Background Prediction of the exposure of neonates, infants and children to xenobiotics is
likely to be more successful using physiologically based pharmacokinetic models than …

The need for left ventricular mass (LVM) normalization to body size is well recognized.
Currently used allometric exponents to normalize LVM may not account for the confounding …

Extensive evidence is available that cardiovascular structure and function, along with other
biological properties that span the range of organism size and speciation, scale with body …

Simulation platforms are increasingly becoming complementary tools for cutting-edge
cardiovascular research. The interplay among structural properties of the arterial wall …

Background—Although cardiac output (CO) plays the vital role of delivering nutrients to body
tissues, few data are available concerning the relations of stroke volume (SV) and CO to …

Cardiac remodeling is typically associated with disease and can lead to heart failure. In
contrast, remodeling that occurs in the athlete's heart is considered an adaptive …

Ratio of stroke volume (SV, M-mode echocardiography) to pulse pressure (PP) has been
proposed as an estimate of total arterial compliance and has been shown to be related to …

Background—It is unclear whether increased left ventricular (LV) mass in overweight
individuals is related to their adiposity or to greater fat-free mass (FFM). Methods and …