Neurodevelopmental outcomes in children with congenital heart disease—what can we impact?

G Wernovsky, DJ Licht - Pediatric Critical Care Medicine, 2016 - journals.lww.com
Objectives: The objectives of this review are to discuss the scope of neurologic injuries in
newborns with congenital heart disease, the mechanisms of injury, including prenatal, pre …

Role of genetic architecture in phenotypic plasticity

P Kovuri, A Yadav, H Sinha - Trends in Genetics, 2023 - cell.com
Phenotypic plasticity, the ability of an organism to display different phenotypes across
environments, is widespread in nature. Plasticity aids survival in novel environments …

The loci of environmental adaptation in a model eukaryote

P Chen, J Zhang - Nature Communications, 2024 - nature.com
While the underlying genetic changes have been uncovered in some cases of adaptive
evolution, the lack of a systematic study prevents a general understanding of the genomic …

Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs

K Schmidlin, S Apodaca, D Newell, A Sastokas… - Elife, 2024 - elifesciences.org
There is growing interest in designing multidrug therapies that leverage tradeoffs to combat
resistance. Tradeoffs are common in evolution and occur when, for example, resistance to …

Biochemical changes, antioxidative profile, and efficacy of the bio-stimulant in plant defense response against Sclerotinia sclerotiorum in common bean (Phasaeolus …

S Kumar, V Shukla, YN Tripathi, M Aamir, K Divyanshu… - Heliyon, 2024 - cell.com
Sclerotinia sclerotiorum, is a highly destructive pathogen with widespread impact on
common bean (Phasaeolus vulgaris L.) worldwide. In this work, we investigated the efficacy …

Quantitative Trait Nucleotides Impacting the Technological Performances of Industrial Saccharomyces cerevisiae Strains

E Peltier, A Friedrich, J Schacherer, P Marullo - Frontiers in Genetics, 2019 - frontiersin.org
The budding yeast Saccharomyces cerevisiae is certainly the prime industrial
microorganism and is related to many biotechnological applications including food …

[PDF][PDF] Revision of Drusinae subfamily (Trichoptera, Limnephilidae): divergence by paraproct and paramere: speciation in isolation by integration

J Oláh, S Beshkov, P Chvojka, C Ciubuc… - Opuscula Zoologica …, 2017 - core.ac.uk
In the last few years we have described over 70 new incipient sibling limnephild species
applying the discovered Trichoptera speciation traits of the paraproct and paramere for …

Pleiotropy, constraint, and modularity in the evolution of life histories: insights from genomic analyses

KA Hughes, J Leips - Annals of the New York Academy of …, 2017 - Wiley Online Library
Multicellular organisms display an enormous range of life history (LH) strategies and present
an evolutionary conundrum; despite strong natural selection, LH traits are characterized by …

RIM15 antagonistic pleiotropy is responsible for differences in fermentation and stress response kinetics in budding yeast

EI Kessi-Perez, S Araos, V García, F Salinas… - FEMS yeast …, 2016 - academic.oup.com
Different natural yeast populations have faced dissimilar selective pressures due to the
heterogeneous fermentation substrates available around the world; this increases the …

Divergent Roles for cAMP–PKA Signaling in the Regulation of Filamentous Growth in Saccharomyces cerevisiae and Saccharomyces bayanus

Ö Kayikci, PM Magwene - G3: Genes, Genomes, Genetics, 2018 - academic.oup.com
Abstract The cyclic AMP–Protein Kinase A (cAMP–PKA) pathway is an evolutionarily
conserved eukaryotic signaling network that is essential for growth and development. In the …