The execution and learning of diverse movements involve neuronal networks distributed
throughout the nervous system. The brainstem and basal ganglia are key for processing …

Classical neurophysiology suggests that the motor cortex (MI) has a unique role in action
control. In contrast, this review presents evidence for multiple parieto-frontal spinal …

Animals make predictions to guide their behavior and update those predictions through
experience. Transient increases in dopamine (DA) are thought to be critical signals for …

The acquisition and execution of motor skills are mediated by a distributed motor network,
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …

Stably recording the electrical activity of the same neurons over the adult life of an animal is
important to neuroscience research and biomedical applications. Current implantable …

Disruption of subthalamic nucleus dynamics in Parkinson's disease leads to impairments
during walking. Here, we aimed to uncover the principles through which the subthalamic …

The classification of neuronal subpopulations has significantly advanced, yet its relevance
for behavior remains unclear. The highly organized flocculus of the cerebellum, known to …

The ability to sequence movements in response to new task demands enables rich and
adaptive behavior. However, such flexibility is computationally costly and can result in …

The shift in control from dorsomedial to dorsolateral striatum during skill and habit formation
has been well established, but whether striatal subregions orchestrate this shift …

Balanced activity of canonical direct D1 and indirect D2 basal ganglia pathways is
considered a core requirement for normal movement, and their imbalance is an etiologic …