The immunopathogenesis of narcolepsy type 1

RS Liblau, D Latorre, BR Kornum… - Nature Reviews …, 2024 - nature.com
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Neurologic adverse events of immune checkpoint inhibitors: a systematic review

A Marini, A Bernardini, GL Gigli, M Valente… - Neurology, 2021 - AAN Enterprises
Objective To define the clinical characteristics, management, and outcome of neurologic
immune-related adverse events (n-irAEs) of immune checkpoint inhibitors (ICIs). Methods …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

Updated diagnostic criteria for paraneoplastic neurologic syndromes

F Graus, A Vogrig, S Muñiz-Castrillo… - Neurology …, 2021 - AAN Enterprises
Objective The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs)
requires an increasing understanding of their clinical, immunologic, and oncologic …

Glial fibrillary acidic protein autoimmunity: a French cohort study

A Gravier-Dumonceau, R Ameli, V Rogemond, A Ruiz… - Neurology, 2022 - AAN Enterprises
Background and Objectives To report the clinical, biological, and imaging features and
clinical course of a French cohort of patients with glial fibrillary acidic protein (GFAP) …

Severe neurological toxicity of immune checkpoint inhibitors: growing spectrum

D Dubey, WS David, KL Reynolds, DF Chute… - Annals of …, 2020 - Wiley Online Library
Expanding use of immune‐checkpoint inhibitors (ICIs) underscores the importance of
accurate diagnosis and timely management of neurological immune‐related adverse events …

Beneficial autoimmunity improves cancer prognosis

L Zitvogel, C Perreault, OJ Finn… - Nature Reviews Clinical …, 2021 - nature.com
Many tumour antigens that do not arise from cancer cell-specific mutations are targets of
humoral and cellular immunity despite their expression on non-malignant cells. Thus, in …

Epidemiology of paraneoplastic neurological syndromes: a population-based study

A Vogrig, GL Gigli, S Segatti, E Corazza, A Marini… - Journal of …, 2020 - Springer
Background The epidemiology of paraneoplastic neurological syndromes (PNS) remains to
be defined. We present here the first population-based incidence study and report the …

Epidemiology of paraneoplastic neurologic syndromes and autoimmune encephalitides in France

J Hébert, B Riche, A Vogrig… - Neurology …, 2020 - AAN Enterprises
Objective To determine the observed and expected incidence rates of paraneoplastic
neurologic syndromes (PNSs) and autoimmune encephalitides (AEs) diagnosed in France …

Neurologic complications of immune checkpoint inhibitors

AM Haugh, JC Probasco… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: Immune checkpoint inhibitors (ICI) are associated with a wide spectrum of
neurologic immune-related adverse events (irAEs) including meningo-encephalitis …