Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities
M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …
Design, classification, and adverse effects of NSAIDs: A review on recent advancements
Inflammation is a hallmark of many diseases, including cancer, neurodegenerative diseases
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …
Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases
The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction
between benzimidazole, aqueous 30% formaldehyde and an amine, the biological …
between benzimidazole, aqueous 30% formaldehyde and an amine, the biological …
Synthesis of Benzimidazole‐Sulfonyl Derivatives and Their Biological Activities
E Mulugeta, Y Samuel - Biochemistry Research International, 2022 - Wiley Online Library
Currently, the synthesis of new compounds with potential bioactivities has become a central
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …
Synthesis, anti-inflammatory, bactericidal activities and docking studies of novel 1, 2, 3-triazoles derived from ibuprofen using click chemistry
KK Angajala, S Vianala, R Macha, M Raghavender… - SpringerPlus, 2016 - Springer
Background Nonsteroidal anti-inflammatory drugs are of vast therapeutic benefit in the
treatment of different types of inflammatory conditions. 1, 2, 3-Triazoles and their derivatives …
treatment of different types of inflammatory conditions. 1, 2, 3-Triazoles and their derivatives …
Antimicrobial potential of benzimidazole derived molecules
Structural resemblance of benzimidazole nucleus with purine nucleus in nucleotides makes
benzimidazole derivatives attractive ligands to interact with biopolymers of a living system …
benzimidazole derivatives attractive ligands to interact with biopolymers of a living system …
Benzimidazole containing acetamide derivatives attenuate neuroinflammation and oxidative stress in ethanol-induced neurodegeneration
Oxidative stress-induced neuroinflammation is the prominent feature of neurodegenerative
disorders, and is characterized by a gradual decline of structure and function of neurons …
disorders, and is characterized by a gradual decline of structure and function of neurons …
Antiplasmodial activity, structure–activity relationship and studies on the action of novel benzimidazole derivatives
Malaria cases and deaths keep being excessively high every year. Some inroads gained in
the last two decades have been eroded especially due to the surge of resistance to most …
the last two decades have been eroded especially due to the surge of resistance to most …
[HTML][HTML] Further and new target-based benzimidazole anthelmintics active against Teladorsagia circumcincta
N Escala, E Valderas-García, MÁ Bardón… - Journal of Molecular …, 2022 - Elsevier
Helminth infections are one of the most prevalent parasitic diseases affecting animals and
humans worldwide. Anthelmintic resistance to the main drugs used to control these …
humans worldwide. Anthelmintic resistance to the main drugs used to control these …