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Vitamin D: classic and novel actions
Background: Classically, vitamin D has been implicated in bone health by promoting
calcium absorption in the gut and maintenance of serum calcium and phosphate …
calcium absorption in the gut and maintenance of serum calcium and phosphate …
[HTML][HTML] Vitamin D: production, metabolism and mechanisms of action
DD Bikle - 2015 - europepmc.org
Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …
Photoprotective properties of vitamin D and lumisterol hydroxyderivatives
We have previously described new pathways of vitamin D3 activation by CYP11A1 to
produce a variety of metabolites including 20 (OH) D3 and 20, 23 (OH) 2 D3. These can be …
produce a variety of metabolites including 20 (OH) D3 and 20, 23 (OH) 2 D3. These can be …
[HTML][HTML] Vitamin D and the skin: Focus on a complex relationship: A review
The “sunshine” vitamin is a hot topic that attracted ample attention over the past decades,
specially that a considerable proportion of the worldwide population are deficient in this …
specially that a considerable proportion of the worldwide population are deficient in this …
Malignant melanoma: An overview, new perspectives, and vitamin D signaling
Simple Summary Despite recent advances in diagnosis and therapy, malignant melanoma
poses a significant problem both to clinicians and cancer researchers due to its resistance to …
poses a significant problem both to clinicians and cancer researchers due to its resistance to …
Nonclassic actions of vitamin D
D Bikle - The Journal of Clinical Endocrinology & Metabolism, 2009 - academic.oup.com
Context: Vitamin D receptors are found in most tissues, not just those participating in the
classic actions of vitamin D such as bone, gut, and kidney. These nonclassic tissues are …
classic actions of vitamin D such as bone, gut, and kidney. These nonclassic tissues are …
Discovering the link between nutrition and skin aging
Skin has been reported to reflect the general inner-health status and aging. Nutrition and its
reflection on skin has always been an interesting topic for scientists and physicians …
reflection on skin has always been an interesting topic for scientists and physicians …
Clinical aspects and molecular diagnostics of skin aging
This contribution will address the effect of aging on skin functions, with a particular focus on
skin permeability, wound healing, angiogenesis, lipogenesis, sweat production, immune …
skin permeability, wound healing, angiogenesis, lipogenesis, sweat production, immune …
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity
JE Cleaver, ET Lam, I Revet - Nature Reviews Genetics, 2009 - nature.com
Mutations in genes on the nucleotide excision repair pathway are associated with diseases,
such as xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy, that involve …
such as xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy, that involve …
Vitamin D and the skin: Physiology and pathophysiology
DD Bikle - Reviews in Endocrine and Metabolic Disorders, 2012 - Springer
The keratinocytes of the skin are unique in being not only the primary source of vitamin D for
the body, but in possessing both the enzymatic machinery to metabolize the vitamin D …
the body, but in possessing both the enzymatic machinery to metabolize the vitamin D …