Polarization-sensitive second harmonic generation microscopy for investigations of diseased collagenous tissues

R Cisek, A Joseph, MA Harvey, D Tokarz - Frontiers in Physics, 2021 - frontiersin.org
The advancement of non-invasive quantitative optical diagnosis techniques such as
polarization-sensitive second harmonic generation microscopy (PSHG) for diseases such as …

[HTML][HTML] A Review of non-linear optical imaging techniques for cancer detection

FJ Ávila - Optics, 2024 - mdpi.com
The World Health Organization (WHO) cancer agency predicts that more than 35 million
cases of cancer will be experienced in 2050, a 77% increase over the 2022 estimate …

Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography

ME Noltes, M Bader, MJH Metman, J Vonk… - European Journal of …, 2023 - Springer
Purpose Patient-tailored management of thyroid nodules requires improved risk of
malignancy stratification by accurate preoperative nodule assessment, aiming to …

Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon

A Peñin-Franch, JA García-Vidal, CM Martínez… - Elife, 2022 - elifesciences.org
The NLRP3 inflammasome coordinates inflammation in response to different pathogen-and
damage-associated molecular patterns, being implicated in different infectious, chronic …

Characterization of pathological stomach tissue using polarization-sensitive second harmonic generation microscopy

H Jeon, MA Harvey, R Cisek, E Bennett… - Biomedical Optics …, 2023 - opg.optica.org
Alterations in collagen ultrastructure between human gastric adenocarcinoma and normal
gastric tissue were investigated using polarization-resolved second harmonic generation …

Compact portable higher harmonic generation microscopy for the real time assessment of unprocessed thyroid tissue

SD Kok, PMR Schaap, L Van Dommelen… - Journal of …, 2024 - Wiley Online Library
During thyroid surgery fast and reliable intra‐operative pathological feedback has the
potential to avoid a two‐stage procedure and significantly reduce health care costs in …

[HTML][HTML] A Mini Review of Quantitative Optical Technologies for Imaging Cell and Tissue Metabolism

A Fan, E Alvarado, A Block, L Shi - Current Opinion in Biomedical …, 2025 - Elsevier
Label-free imaging techniques, with their non-destructive, dye-free operation, and broad
detection capabilities, have rapidly advanced and found application in biological tissue …

Dental age estimation using multiphoton microscopy: a potential tool for forensic science

JM Bueno, RM Martínez-Ojeda… - BioMed Research …, 2022 - Wiley Online Library
Normal aging affects the different structures of teeth, in particular, the dentine. These
changes are useful in forensic disciplines as a tool for age estimation. Although multiphoton …

[HTML][HTML] Collagen organization, polarization sensitivity and image quality in human corneas using second harmonic generation microscopy

JM Bueno, RM Martínez-Ojeda, I Yago, FJ Ávila - Photonics, 2022 - mdpi.com
In this paper, a Second-Harmonic-Generation (SHG) microscope was used to study the
relationship between collagen structural arrangement, image quality and polarization …

Analysis of age-related changes in the left ventricular myocardium with multiphoton microscopy

JM Bueno, RM Martínez-Ojeda… - Biomedical Optics …, 2024 - opg.optica.org
Aging induces cardiac remodeling, resulting in an increase in the risk of suffering heart
diseases, including heart failure. Collagen deposition increases with age and, together with …