Androgen (dihydrotestosterone)–mediated regulation of food intake and obesity in female mice

N Kanaya, S Vonderfecht, S Chen - The Journal of steroid biochemistry and …, 2013 - Elsevier
To better understand how elevated androgen levels regulate food intake and obesity in
females, we treated ovariectomized female mice with dihydrotestosterone (DHT)(non …

Long-term oral administration of osteocalcin induces insulin resistance in male mice fed a high-fat, high-sucrose diet

Y Yasutake, A Mizokami… - American Journal …, 2016 - journals.physiology.org
Uncarboxylated osteocalcin (GluOC), a bone-derived hormone, regulates energy
metabolism by stimulating insulin secretion, pancreatic β-cell proliferation, and adiponectin …

Estrogen Regulates Mitochondrial Activity Through Inducing Brain‐Derived Neurotrophic Factor Expression in Skeletal Muscle

MCL Tse, BPS Pang, X Bi, TX Ooi… - Journal of Cellular …, 2025 - Wiley Online Library
Estrogen is an essential hormone for the development and functional activities of
reproductive organs. Recent studies showed that estrogen signaling is also an important …

[HTML][HTML] Low Testosterone and High Leptin Activate PPAR Signaling to Induce Adipogenesis and Promote Fat Deposition in Caponized Ganders

M Lei, Y Li, J Li, J Liu, Z Dai, R Chen, H Zhu - International Journal of …, 2024 - mdpi.com
Low or insufficient testosterone levels caused by caponization promote fat deposition in
animals. However, the molecular mechanism of fat deposition in caponized animals remains …

Influence of age on leptin induced skeletal muscle signalling

A Guadalupe‐Grau, S Larsen, B Guerra… - Acta …, 2014 - Wiley Online Library
Aim Age associated fat mass accumulation could be because of dysregulation of leptin
signalling in skeletal muscle. Thus, we investigated total protein expression and …

Circulating sex steroids coregulate adipose tissue immune cell populations in healthy men

KB Rubinow, JH Chao, D Hagman… - American Journal …, 2017 - journals.physiology.org
Male hypogonadism results in changes in body composition characterized by increases in
fat mass. Resident immune cells influence energy metabolism in adipose tissue and could …

Effects of caponization on growth performance and carcass composition of Yangzhou ganders

M Lei, X Qu, Z Dai, R Chen, H Zhu, Z Shi - Animals, 2022 - mdpi.com
Simple Summary Goose meat is recognized as one of the healthiest foods. Goose capons
are specially bred and consumed in several parts of China for their high-quality meat …

Lack of AR in LepRb cells disrupts ambulatory activity and neuroendocrine axes in a sex-specific manner in mice

AL Cara, MG Myers Jr, CF Elias - Endocrinology, 2020 - academic.oup.com
Disorders of androgen imbalance, such as hyperandrogenism in females or
hypoandrogenism in males, increase risk of visceral adiposity, type 2 diabetes, and infertility …

Impairment of testes development in Yangzhou ganders by augmentation of leptin receptor signaling

MM Lei, ZC Dai, HX Zhu, R Chen, Z Chen, CR Shao… - Theriogenology, 2021 - Elsevier
The aim of this study was to determine the cellular and molecular mechanisms of leptin
(LEP) and the leptin receptor (LEPR) in testicular development of prepubertal ganders. In an …

Role of Androgen Receptor in Hypothalamic Regulation of Metabolism and Reproduction

A Cara - 2021 - deepblue.lib.umich.edu
Androgens are steroid hormones that have sex-specific effects on regulation of metabolic
and reproductive physiology. Androgens primarily act upon nuclear hormone receptors …