Extensive research has shown that interleukin 6 (IL-6) is a multifunctional molecule that is
both proinflammatory and anti-inflammatory, depending on the context. Here, we combine …

Inhibited immune response and low levels of delivery restrict starvation cancer therapy
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …

To date, the construction of heterogeneous interfaces between sonosensitizers and other
semiconductors or noble metals has aroused increasing attention, owing to an enhanced …

The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …

The intense metabolism of cancer cells leads to hypoxia and lack of crucial nutrients in the
tumor microenvironment, which hinders the function of immune cells. We designed a …

Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …

Cells communicate with their environment via surface proteins and secreted factors.
Unconventional protein secretion (UPS) is an evolutionarily conserved process, via which …

Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …

Excessive consumption of fructose in the Western diet contributes to cancer development.
However, it is still unclear how cancer cells coordinate glucose and fructose metabolism …