Migraine is a neurovascular disorder that affects over 1 billion people worldwide. Its
widespread prevalence, and associated disability, have a range of negative and substantial …

Magnesium plays an important role in many physiological functions. Habitually low intakes
of magnesium and in general the deficiency of this micronutrient induce changes in …

Background Primary headache disorders are common and burdensome conditions. They
are associated to several comorbidities, such as cardiovascular or psychiatric ones, which …

Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling
attacks of headache and accompanying symptoms, including aura. The aetiology is …

Migraine is two to three times more prevalent in women than men, and women report a
longer attack duration, increased risk of headache recurrence, greater disability, and a …

Migraine is a complex condition in which genetic predisposition interacts with other
biological and environmental factors determining its course. A hyperresponsive brain cortex …

Regular or frequent use of analgesics and acute antimigraine drugs can increase the
frequency of headache, and induce the transition from episodic to chronic headache or …

Background The burden of headache disorders, and of migraine in particular, is multifaceted
and fragmented. The aim of this narrative review is to provide a description the main topics …

Background There is an unmet need of pharmacological and non-pharmacological
treatment options for migraine patients. Exercise can be used in the treatment of several …

Objective While there are several trials that support the efficacy of various drugs for migraine
prophylaxis against placebo, there is limited evidence addressing the comparative safety …