Cellular host factors for SARS-CoV-2 infection
Abstract The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives
and caused a global economic crisis. No effective antiviral drugs are currently available to …
and caused a global economic crisis. No effective antiviral drugs are currently available to …
Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …
The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions
R Oughtred, J Rust, C Chang, BJ Breitkreutz… - Protein …, 2021 - Wiley Online Library
Abstract The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.
org) is an open‐access database resource that houses manually curated protein and …
org) is an open‐access database resource that houses manually curated protein and …
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
The emergence and global spread of SARS-CoV-2 has resulted in the urgent need for an in-
depth understanding of molecular functions of viral proteins and their interactions with the …
depth understanding of molecular functions of viral proteins and their interactions with the …
A proteome-scale map of the SARS-CoV-2–human contactome
Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Abstract Treatment options for COVID‐19, caused by SARS‐CoV‐2, remain limited.
Understanding viral pathogenesis at the molecular level is critical to develop effective …
Understanding viral pathogenesis at the molecular level is critical to develop effective …
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
B Meyer, J Chiaravalli, S Gellenoncourt… - Nature …, 2021 - nature.com
SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over
170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and …
170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and …
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
LA Armstrong, SM Lange, V Dee Cesare, SP Matthews… - PloS one, 2021 - journals.plos.org
Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and
plays important roles in the viral life cycle. Being a large, multidomain, transmembrane …
plays important roles in the viral life cycle. Being a large, multidomain, transmembrane …
Interactomes of SARS‐CoV‐2 and human coronaviruses reveal host factors potentially affecting pathogenesis
Host–virus protein–protein interactions play key roles in the life cycle of severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). We conducted a comprehensive …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). We conducted a comprehensive …
Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
E Murigneux, L Softic, C Aubé, C Grandi… - Nature …, 2024 - nature.com
Considerable progress has been made in understanding the molecular host-virus battlefield
during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed …
during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed …