Monitoring of tumor vascular normalization: the key points from basic research to clinical application

W Li, YY Quan, Y Li, L Lu, M Cui - Cancer Management and …, 2018 - Taylor & Francis
Tumor vascular normalization alleviates hypoxia in the tumor microenvironment, reduces the
degree of malignancy, and increases the efficacy of traditional therapy. However, the time …

PET/MRI of central nervous system: current status and future perspective

ZL Yang, LJ Zhang - European radiology, 2016 - Springer
Imaging plays an increasingly important role in the early diagnosis, prognosis prediction and
therapy response evaluation of central nervous system (CNS) diseases. The newly …

Change in 18F-Fluoromisonidazole PET Is an Early Predictor of the Prognosis in the Patients with Recurrent High-Grade Glioma Receiving Bevacizumab Treatment

S Yamaguchi, K Hirata, T Toyonaga, K Kobayashi… - PLoS …, 2016 - journals.plos.org
Background Bevacizumab (BEV), a humanized monoclonal antibody, become a currently
important chemotherapeutic option for the patients with recurrent glioma. The aim of this …

Recent update on PET/CT Radiotracers for Imaging Cerebral Glioma

D Kim, SH Lee, HS Hwang, SJ Kim, M Yun - Nuclear Medicine and …, 2024 - Springer
Positron emission tomography/computed tomography (PET/CT) has dramatically altered the
landscape of noninvasive glioma evaluation, offering complementary insights to those …

The validation path of hypoxia PET imaging: focus on brain tumours

N Quartuccio, MC Asselin - Current Medicinal Chemistry, 2018 - ingentaconnect.com
Background: Gliomas are brain tumours arising from the glia, the supportive tissue of the
central nervous system (CNS), and constitute the commonest primary malignant brain …

Clinical Theranostics in Recurrent Gliomas: A Review

AR Hoggarth, S Muthukumar, SM Thomas, J Crowley… - Cancers, 2024 - mdpi.com
Simple Summary This paper discusses the challenges in treating high-grade gliomas,
particularly glioblastomas, which are aggressive brain tumors with high recurrence rates. It …

Usefulness of positron emission tomographic studies for gliomas

K MiyaKe, D Ogawa, M OKaDa… - Neurologia medico …, 2016 - jstage.jst.go.jp
Non-invasive positron emission tomography (PET) enables the measurement of metabolic
and molecular processes with high sensitivity. PET plays a significant role in the diagnosis …

A comparison of PET tracers in recurrent high-grade gliomas: a systematic review

S Muthukumar, J Darden, J Crowley, M Witcher… - International Journal of …, 2022 - mdpi.com
Humans with high-grade gliomas have a poor prognosis, with a mean survival time of just 12–
18 months for patients who undergo standard-of-care tumor resection and adjuvant therapy …

State of the art treatment and surveillance imaging of glioblastomas

S Margiewicz, C Cordova, AS Chi, R Jain - Seminars in Roentgenology, 2018 - Elsevier
Glioblastoma (GBM) is the most common malignant brain tumor in the United States and the
world with about 15,000 and 210,000 new cases diagnosed each year, respectively. 1 For …

In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma

A Hawkins-Daarud, R Rockne… - Journal of the …, 2015 - royalsocietypublishing.org
Recently, two phase III studies of bevacizumab, an anti-angiogenic, for newly diagnosed
glioblastoma (GBM) patients were released. While they were unable to statistically …