Plant-based phytochemicals as possible alternative to antibiotics in combating bacterial drug resistance

HMA AlSheikh, I Sultan, V Kumar, IA Rather… - Antibiotics, 2020 - mdpi.com
The unprecedented use of antibiotics that led to development of resistance affect human
health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases …

Escherichia coli biofilm: development and therapeutic strategies

G Sharma, S Sharma, P Sharma… - Journal of applied …, 2016 - academic.oup.com
Escherichia coli biofilm consists of a bacterial colony embedded in a matrix of extracellular
polymeric substances (EPS) which protects the microbes from adverse environmental …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

Metformin restores tetracyclines susceptibility against multidrug resistant bacteria

Y Liu, Y Jia, K Yang, R Li, X **ao, K Zhu… - Advanced …, 2020 - Wiley Online Library
Highly persistent incidence of multidrug resistant (MDR) bacterial pathogens constitutes a
global burden for public health. An alternative strategy to alleviate such a crisis is to identify …

Inhibiting bacterial drug efflux pumps via phyto-therapeutics to combat threatening antimicrobial resistance

V Shriram, T Khare, R Bhagwat, R Shukla… - Frontiers in …, 2018 - frontiersin.org
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …

Drug efflux pump inhibitors: a promising approach to counter multidrug resistance in Gram-negative pathogens by targeting AcrB protein from AcrAB-TolC multidrug …

R Alenazy - Biology, 2022 - mdpi.com
Simple Summary Multidrug-resistant bacterial infections, especially that caused by Gram-
negative bacteria, have posed serious health issues worldwide. Bacteria have different …

[HTML][HTML] Evolving biofilm inhibition and eradication in clinical settings through plant-based antibiofilm agents

E Silva, JA Teixeira, MO Pereira, CMR Rocha… - Phytomedicine, 2023 - Elsevier
Background After almost 100 years since evidence of biofilm mode of growth and decades
of intensive investigation about their formation, regulatory pathways and mechanisms of …

Efflux in Gram-negative bacteria: what are the latest opportunities for drug discovery?

T Gil-Gil, P Laborda, LE Ochoa-Sánchez… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The resistance-nodulation-division (RND) family is the most important group of
multidrug efflux pumps in Gram-negative bacteria. Their inhibition increases the …

Embelin-loaded chitosan gold nanoparticles interact synergistically with ciprofloxacin by inhibiting efflux pumps in multidrug-resistant Pseudomonas aeruginosa and …

T Khare, S Mahalunkar, V Shriram, S Gosavi… - Environmental …, 2021 - Elsevier
A global upsurge in emergence and spread of antibiotic resistance (ABR) in bacterial
populations is a serious threat for human health. Unfortunately, ABR is no longer confined to …

Traditional uses, phytochemistry, and pharmacology of the genus Acer (maple): A review

W Bi, Y Gao, J Shen, C He, H Liu, Y Peng… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance The genus Acer (Aceraceae), commonly known
as maple, comprises approximately 129 species that primarily grow in the northern …