Machine learning methods for small data challenges in molecular science

B Dou, Z Zhu, E Merkurjev, L Ke, L Chen… - Chemical …, 2023 - ACS Publications
Small data are often used in scientific and engineering research due to the presence of
various constraints, such as time, cost, ethics, privacy, security, and technical limitations in …

Applied machine learning as a driver for polymeric biomaterials design

SM McDonald, EK Augustine, Q Lanners… - Nature …, 2023 - nature.com
Polymers are ubiquitous to almost every aspect of modern society and their use in medical
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …

Chemformer: a pre-trained transformer for computational chemistry

R Irwin, S Dimitriadis, J He… - … Learning: Science and …, 2022 - iopscience.iop.org
Transformer models coupled with a simplified molecular line entry system (SMILES) have
recently proven to be a powerful combination for solving challenges in cheminformatics …

Predictive chemistry: machine learning for reaction deployment, reaction development, and reaction discovery

Z Tu, T Stuyver, CW Coley - Chemical science, 2023 - pubs.rsc.org
The field of predictive chemistry relates to the development of models able to describe how
molecules interact and react. It encompasses the long-standing task of computer-aided …

Current strategies to address data scarcity in artificial intelligence-based drug discovery: A comprehensive review

A Gangwal, A Ansari, I Ahmad, AK Azad… - Computers in Biology …, 2024 - Elsevier
Artificial intelligence (AI) has played a vital role in computer-aided drug design (CADD). This
development has been further accelerated with the increasing use of machine learning (ML) …

Molecule edit graph attention network: modeling chemical reactions as sequences of graph edits

M Sacha, M Błaz, P Byrski… - Journal of Chemical …, 2021 - ACS Publications
The central challenge in automated synthesis planning is to be able to generate and predict
outcomes of a diverse set of chemical reactions. In particular, in many cases, the most likely …

An ensemble transfer learning strategy for production prediction of shale gas wells

W Niu, Y Sun, X Zhang, J Lu, H Liu, Q Li, Y Mu - Energy, 2023 - Elsevier
In order to overcome the training data insufficient problem of model for shale gas wells
production prediction in new block, this study proposes a transfer learning strategy of …

Enhancing ECG-based heart age: impact of acquisition parameters and generalization strategies for varying signal morphologies and corruptions

MY Ansari, M Qaraqe, R Righetti, E Serpedin… - Frontiers in …, 2024 - frontiersin.org
Electrocardiogram (ECG) is a non-invasive approach to capture the overall electrical activity
produced by the contraction and relaxation of the cardiac muscles. It has been established …

Artificial intelligence in reaction prediction and chemical synthesis

V Venkatasubramanian, V Mann - Current Opinion in Chemical Engineering, 2022 - Elsevier
Recent years have seen a sudden spurt in the use of artificial intelligence (AI) methods for
computational reaction modeling and prediction. Given the diversity of the techniques, we …

[HTML][HTML] User-friendly and industry-integrated AI for medicinal chemists and pharmaceuticals

O Kapustina, P Burmakina, N Gubina, N Serov… - Artificial Intelligence …, 2024 - Elsevier
Artificial intelligence has brought crucial changes to the whole field of natural sciences.
Myriads of machine learning algorithms have been developed to facilitate the work of …