Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

The single largest risk factor for etiology of neurodegenerative diseases like Alzheimer's
disease is increased age. Therefore, understanding the changes that occur as a result of …

In the last decade, positron emission tomography (PET) and single-photon emission
computed tomography (SPECT) in in vivo imaging has attempted to demonstrate the …

The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

Evidence of copper's (Cu) involvement in Alzheimer's disease (AD) is available, but
information on Cu involvement in microglia and astrocytes during the course of AD has yet to …

Alzheimer's disease (AD) is a kind of neurodegenerative diseases characterized by beta-
amyloid deposition and neurofibrillary tangles and is also the main cause of dementia …

Microglia, the intrinsic neuroimmune cells residing in the central nervous system (CNS),
exert a pivotal influence on brain development, homeostasis, and functionality …

In mammals, myeloid cells help maintain the homeostasis of peripheral metabolic tissues,
and their immunologic dysregulation contributes to the progression of obesity and …

Objectives: Neuroinflammation is a complex inflammatory process in the central nervous
system (CNS) where microglia may play a critical role. GPETAFLR is a peptide isolated from …

Progressive memory loss and cognitive dysfunction, encompassing deficits in learning,
memory, problem-solving, spatial reasoning, verbal expression are characteristics of …