Global hydrocephalus epidemiology and incidence: systematic review and meta-analysis
OBJECTIVE Hydrocephalus is one of the most common brain disorders, yet a reliable
assessment of the global burden of disease is lacking. The authors sought a reliable …
assessment of the global burden of disease is lacking. The authors sought a reliable …
Hydrocephalus in children
Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …
Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus
Post-hemorrhagic hydrocephalus (PHH) refers to a life-threatening accumulation of
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An …
cerebrospinal fluid (CSF) that occurs following intraventricular hemorrhage (IVH). An …
The choroid plexus and its role in the pathogenesis of neurological infections
The choroid plexus is situated at an anatomically and functionally important interface within
the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the …
the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the …
The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Background Cerebrospinal fluid (CSF) is an ultra-filtrated colorless brain fluid that circulates
within brain spaces like the ventricular cavities, subarachnoid space, and the spine. Its …
within brain spaces like the ventricular cavities, subarachnoid space, and the spine. Its …
De novo mutation in genes regulating neural stem cell fate in human congenital hydrocephalus
Congenital hydrocephalus (CH), featuring markedly enlarged brain ventricles, is thought to
arise from failed cerebrospinal fluid (CSF) homeostasis and is treated with lifelong surgical …
arise from failed cerebrospinal fluid (CSF) homeostasis and is treated with lifelong surgical …
The genetic landscape of familial congenital hydrocephalus
Objective Congenital hydrocephalus is an important birth defect, the genetics of which
remains incompletely understood. To date, only 4 genes are known to cause Mendelian …
remains incompletely understood. To date, only 4 genes are known to cause Mendelian …
A neural stem cell paradigm of pediatric hydrocephalus
Pediatric hydrocephalus, the leading reason for brain surgery in children, is characterized by
enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) …
enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) …