Natriuretic Peptide Signaling in Uterine Biology and Preeclampsia

Q Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
Endometrial decidualization is a uterine process essential for spiral artery remodeling,
embryo implantation, and trophoblast invasion. Defects in endometrial decidualization and …

Preeclampsia: A comprehensive review

M Ali, M Ahmed, M Memon, F Chandio, Q Shaikh… - Clinica Chimica …, 2024 - Elsevier
Preeclampsia (PE) is a life-threatening disease of pregnancy and a prominent cause of
neonatal and maternal mortality and morbidity. PE affects approximately 5–10% of …

Genetic associations of circulating cardiovascular proteins with gestational hypertension and preeclampsia

A Schuermans, B Truong, M Ardissino… - JAMA …, 2024 - jamanetwork.com
Importance Hypertensive disorders of pregnancy (HDPs), including gestational hypertension
and preeclampsia, are important contributors to maternal morbidity and mortality worldwide …

Pregnancy-Induced Hypertensive Disorders predictors among pregnant and delivery mothers receiving care in public health institutions in Sidama, Ethiopia: a …

GT Bune - BMC Pregnancy and Childbirth, 2024 - Springer
Abstract Background Pregnancy-Induced Hypertensive Disorders (PIHD) include conditions
like Pre-Eclampsia, Eclampsia, and Gestational Hypertension, impacting 5–10% of …

[HTML][HTML] Bidirectional Mendelian Randomization Analysis of Genetic Proxies of Plasma Fatty Acids and Pre-Eclampsia Risk

J Zhou, S Jiang, D Liu, X Li, Z Zhou, Z Wang, H Wang - Nutrients, 2024 - mdpi.com
Background: Previous studies have reported associations between fatty acids and the risk of
pre-eclampsia. However, the causality of these associations remains uncertain. This study …

Proteome-and Transcriptome-Wide Genetic Analysis Identifies Biological Pathways and Candidate Drug Targets for Preeclampsia

M Ardissino, B Truong, EAW Slob… - Circulation: Genomic …, 2024 - ahajournals.org
BACKGROUND: Preeclampsia is a leading cause of maternal and perinatal morbidity and
mortality. However, the current understanding of its underlying biological pathways remains …

Recent advances in understanding the mechanistic role of transient receptor potential ion channels in hypertension.

FJ Rios, RD Sarafian, LL Camargo… - Canadian Journal of …, 2023 - Elsevier
The transient receptor potential (TRP) channel superfamily is a group of non-selective cation
channels functioning as cellular sensors for a wide range of physical, chemical and …

[HTML][HTML] Placental Origins of Preeclampsia: Insights from Multi-Omic Studies

C Cao, R Saxena, KJ Gray - International Journal of Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
Preeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality
worldwide, with the placenta playing a central role in disease pathophysiology. This review …

From Biobanking to Personalized Medicine: the journey of the Estonian Biobank

L Milani, M Alver, S Laur, S Reisberg, T Haller… - medRxiv, 2024 - medrxiv.org
Large biobanks have set a new standard for research and innovation in human genomics
and implementation of personalised medicine. The Estonian Biobank was founded a quarter …

Genetic Insights and Neonatal Outcomes in Preeclampsia and Eclampsia: A Detailed Analysis of the RS5707 Genotype

FG Socol, ES Bernad, M Craina, SA Abu-Awwad… - Diagnostics, 2024 - mdpi.com
Background: Preeclampsia (PE) and eclampsia (E) are severe pregnancy complications
with significant maternal and neonatal health impacts. This study explores the association of …