A review of the biological activities of lactoferrin: Mechanisms and potential applications

R Hong, A **e, C Jiang, Y Guo, Y Zhang, J Chen… - Food & Function, 2024 - pubs.rsc.org
Lactoferrin, a multifunctional iron-binding protein found in milk and other body fluids,
possesses numerous biological activities. The functional activity of lactoferrin lies not only in …

Time to kill and time to heal: the multifaceted role of lactoferrin and lactoferricin in host defense

A Ohradanova-Repic, R Praženicová, L Gebetsberger… - Pharmaceutics, 2023 - mdpi.com
Lactoferrin is an iron-binding glycoprotein present in most human exocrine fluids,
particularly breast milk. Lactoferrin is also released from neutrophil granules, and its …

The potential of lactoferrin as antiviral and immune-modulating agent in viral infectious diseases

F Eker, H Duman, M Ertürk, S Karav - Frontiers in immunology, 2024 - frontiersin.org
Emerging infectious diseases are caused by unpredictable viruses with the dangerous
potential to trigger global pandemics. These viruses typically initiate infection by utilizing the …

Biomedical and nutritional applications of lactoferrin

C Coccolini, E Berselli, C Blanco-Llamero… - International Journal of …, 2023 - Springer
Lactoferrin (Lf) is a glycoprotein belonging to the transferrin family, which can be found in
mammalian milk. It was first isolated from bovine milk in the 1930s, and later in the 1960s, it …

[HTML][HTML] Lactoferrin: A Promising Therapeutic Molecule against Human Papillomavirus

M Kaplan, M Baktıroğlu, AE Kalkan, AA Canbolat… - Nutrients, 2024 - mdpi.com
Lactoferrin is a multifunctional glycoprotein naturally found in mammalian secretions,
predominantly in colostrum and milk. As a key component of dairy foods, lactoferrin …

Green synthesis, characterization, anti-SARS-CoV-2 entry, and replication of lactoferrin-coated zinc nanoparticles with halting lung fibrosis induced in adult male …

EM El-Fakharany, YA El-Maradny, M Ashry… - Scientific Reports, 2023 - nature.com
The ethanolic extract of Coleus forskohlii Briq leaves was employed in the green synthesis
of zinc nanoparticles (Zn-NPs) by an immediate, one-step, and cost-effective method in the …

Liposomal lactoferrin exerts antiviral activity against HCoV-229E and SARS-CoV-2 pseudoviruses in vitro

S Andreu, I Ripa, R Bello-Morales, JA López-Guerrero - Viruses, 2023 - mdpi.com
A limited number of effective therapies are currently available to treat human coronavirus
SARS-CoV-2 and other human coronaviruses, which are responsible for nearly a third of …

Potential of lactoferrin in the treatment of lung diseases

K Kaczyńska, M Jampolska, P Wojciechowski… - Pharmaceuticals, 2023 - mdpi.com
Lactoferrin (LF) is a multifunctional iron-binding glycoprotein that exhibits a variety of
properties, such as immunomodulatory, anti-inflammatory, antimicrobial, and anticancer, that …

Immunomodulatory effect of bovine lactoferrin during SARS-CoV-2 infection

AMV Silva, TL Machado, RS Nascimento… - Frontiers in …, 2024 - frontiersin.org
Introduction Lactoferrin (Lf) is an important immunomodulator in infections caused by
different agents. During SARS-CoV-2 infection, Lf can hinder or prevent virus access to the …

Global bibliometric and visualized analysis of research on lactoferrin from 1978 to 2024

H Gu, Y Wang, Y Wang, L Ding, W Huan… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Lactoferrin (LF) is an iron‐bound protein with a molecular weight of about 80 kDa. LF
has many biological functions such as antibacterial, antiviral, immunomodulatory, and …