Design by nature: emerging applications of native liver extracellular matrix for cholangiocyte organoid-based regenerative medicine

J Willemse, LJW van der Laan, J de Jonge… - Bioengineering, 2022 - mdpi.com
Organoid technology holds great promise for regenerative medicine. Recent studies show
feasibility for bile duct tissue repair in humans by successfully transplanting cholangiocyte …

A review of machine perfusion strategies in liver transplantation

A Banker, N Bhatt, PS Rao, P Agrawal, M Shah… - Journal of Clinical and …, 2023 - Elsevier
The acceptance of liver transplantation as the standard of care for end-stage liver diseases
has led to a critical shortage of donor allografts. To expand the donor organ pool, many …

Liver ultrasound histotripsy: novel analysis of the histotripsy site cell constituents with implications for histotripsy application in cell transplantation and cancer therapy

S Froghi, MO De Andrade, LM Hadi, P Gelat, H Rashidi… - Bioengineering, 2023 - mdpi.com
Introduction: Allogenic hepatocyte transplantation is an attractive alternative to whole-organ
transplantation, particularly for the treatment of metabolic disorders and acute liver failure …

Endothelial Cell Replacement of Human Veins, Modeling Vascular Repair and Endothelial Cell Chimerism

H Tejeda-Mora, Y den Hartog, IJ Schurink… - Stem Cells and …, 2024 - liebertpub.com
Allogeneic transplant organs are potentially highly immunogenic. The endothelial cells
(ECs) located within the vascular system serve as the primary interface between the …

Current Landscape and Opportunities in the development of Bioengineered In-Vitro Vascularized Liver Tissue Models

K Kumari, A Sanyal, P Rawat, V Kumar, M Garg… - Bioprinting, 2024 - Elsevier
The complications in liver functioning arising due to hepatic disorders are a major
contributor of mortality worldwide, with transplantation being the only resort for patients with …

Assessment of the efficacy and safety of a novel pharmacological strategy designed to enhance liver regeneration following tumour resection

T Bunday - 2023 - search.proquest.com
Liver cancer, encompassing both primary cancers such as hepatocellular carcinoma (HCC),
and secondary cancers such as colorectal liver metastasis (CRLM), is becoming …