Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

The thalamus, with its cortical, subcortical, and cerebellar connections, is a critical node in
networks supporting cognitive functions known to decline in normal aging, including …

Background Executive cognitive functions, including working memory, cognitive flexibility,
and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated …

The thalamus and its nuclei are largely indistinguishable on standard T1 or T2 weighted
MRI. While diffusion tensor imaging based methods have been proposed to segment the …

Brain circuitry underlying cognition, emotion, and perception is abnormal in schizophrenia.
There is considerable evidence that the neuropathology of schizophrenia includes the …

The function of the human mediodorsal thalamic nucleus (MD) has so far eluded a clear
definition in terms of specific cognitive processes and tasks. Although it was at first proposed …

Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …

Quantitative magnetic resonance imaging generates images of meaningful physical or
chemical variables measured in physical units that allow quantitative comparisons between …

The aging brain undergoes several anatomical changes that can be measured with
Magnetic Resonance Imaging (MRI). Early studies using lower field strengths have …

MRI-guided focused ultrasound thalamotomy has been shown to be an effective treatment
for medication refractory essential tremor. Here, we report a clinical-radiological analysis of …