Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against
COVID-19. SARS-CoV-2 main protease (Mpro, 3CLpro) and papain-like protease (PLpro) …
COVID-19. SARS-CoV-2 main protease (Mpro, 3CLpro) and papain-like protease (PLpro) …
Cerium-Doped Manganese Oxide Catalyst for the Oxidative Coupling Synthesis of Fluorescent 2-Amino-1,9-dimethyl-3H-phenoxazin-3-one Using Atmospheric …
F Sun, J Qin, X Cao, X Zhang, X Tang… - ACS Sustainable …, 2022 - ACS Publications
The heterogeneous catalytic oxidative coupling synthesis of 2-amino-3 H-phenoxazin-3-one
(APXO) from the oxidative coupling of 2-aminophenol has important practical significance …
(APXO) from the oxidative coupling of 2-aminophenol has important practical significance …
TEMPO-catalyzed electrochemical dehydrogenative cyclocondensation of o-aminophenols: synthesis of aminophenoxazinones as antiproliferative agents
J Zhou, ZY Ma, C Shonhe, SH Ji, YR Cai - Green Chemistry, 2021 - pubs.rsc.org
The aminophenoxazinone core is widely prevalent in natural products, dyes and
pharmaceutical molecules. We report here a TEMPO-catalyzed electrosynthetic method …
pharmaceutical molecules. We report here a TEMPO-catalyzed electrosynthetic method …
Synthesis of aminophenoxazinones and evaluation of their phytotoxicity in the search for new natural herbicides
Natural products have been postulated as an alternative to the use of synthetic herbicides in
pest control. The latter compounds have caused numerous problems and these include the …
pest control. The latter compounds have caused numerous problems and these include the …
Reaction of bis [(2-chlorocarbonyl) phenyl] diselenide with phenols, aminophenols, and other amines towards diphenyl diselenides with antimicrobial and antiviral …
M Giurg, A Gołąb, J Suchodolski, R Kaleta… - Molecules, 2017 - mdpi.com
A reaction of bis [(2-chlorocarbonyl) phenyl] diselenide with various mono and
bisnucleophiles such as aminophenols, phenols, and amines have been studied as a …
bisnucleophiles such as aminophenols, phenols, and amines have been studied as a …
[PDF][PDF] Synthesis of new alkylated and methoxylated analogues of ebselen with antiviral and antimicrobial properties
M Pietka-Ottlik, M Burda-Grabowska, M Wozna… - Arkivoc, 2017 - pdfs.semanticscholar.org
A series of new mono and disubstituted alkylated and methoxylated benzisoselanzol-3 (2H)-
ones and bis (2-carbamoylaryl) diselenides were prepared in yields ranging from 55% to …
ones and bis (2-carbamoylaryl) diselenides were prepared in yields ranging from 55% to …
Laccase‐Mimicking Syntheses of Phenoxazinones by Aerobic Oxidative Homo‐and Hetero‐Dimerizations of Aminophenols
W Duan, W Li, Q Tang, Y Zhao, X Guo… - ChemistrySelect, 2021 - Wiley Online Library
To pursue a sustainable enzyme‐liking approach, a laccase‐mimicking model that utilized
natural low‐toxic gallic acid as an organocatalyst was developed for efficient aerobic …
natural low‐toxic gallic acid as an organocatalyst was developed for efficient aerobic …
Oxidation of 2-aminophenol to 2-amino-3H-phenoxazin-3-one with monochloramine in aqueous environment: A new method for APO synthesis?
O Abou Mehrez, F Dossier-Berne, B Legube - Chemosphere, 2016 - Elsevier
Abstract Reaction of 2-aminophenol (2AP) with monochloramine in aqueous solution was
investigated at pH 8.5 and 25° C, with an excess of monochloramine. 2-Amino-3H …
investigated at pH 8.5 and 25° C, with an excess of monochloramine. 2-Amino-3H …
Silver(I) complex with 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazin-3-one (Phx-1) ligand: crystal structure, vibrational spectra and biological studies
The first metal complex of Phx-1 ligand, bis (2-amino-4, 4α-dihydro-4α, 7-dimethyl-3 H-
phenoxazin-3-one) nitratosilver (I),[Ag (Phx-1) 2NO3], has been obtained and investigated …
phenoxazin-3-one) nitratosilver (I),[Ag (Phx-1) 2NO3], has been obtained and investigated …
Expansion of the aromatic part of Cinchona alkaloids. Annulation of quinolines with phenoxazine motifs
M Wąsińska-Kałwa, M Giurg, PJ Boratyński… - Tetrahedron, 2018 - Elsevier
An oxidative cross-coupling strategy for quinoline ring annulation in Cinchona alkaloids has
been developed. Key-reaction optimization by changing oxidants and adjusting the …
been developed. Key-reaction optimization by changing oxidants and adjusting the …